Migraines in youths with low Vitamin D wonderfully treated by Vitamin D

Created July 2019

Evaluation of Vitamin D Levels and Response to Therapy of Childhood Migraine.

Medicina (Kaunas). 2019 Jun 28;55(7). pii: E321. doi: 10.3390/medicina55070321.

Kılıç B1, Kılıç M2.

1 Dept of Child Neurology, University of Health Sciences, Derince Training and Research Hospital, 41900 Kocaeli, Turkey. betulklc82@gmail.com.
2 Dept of Neurosurgery, University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, 34371 Istanbul, Turkey. kilicnrs@gmail.com.

6 month trial on migraine youths of average age 13 who had < 20ng level of vitamin D Started with 2,000 IU for 2 months, then 600 to 1,000 IU daily for 4 months Expect that they would have had even better success by Using larger dose sizes so as to get most of them >30 ng - Larger doses especially for those who were heavier/overweight Adding Magnesium and Zinc Also expect that the Migraines would have been reduced in a few weeks if they had used a loading dose of Vitamin D Note: Both Migraines and Cluster headaches in adults have been very succesfully treated by Vitamin D and Magnesium --- 1. See also VitaminDWiki Headache category has the following | | | | | | --- | --- | --- | --- | | Metal | Migraine | No Migraine | Ratio | | Cadmium | 0.36 ug | 0.09 ug | 4X MORE if decrease | | Iron | 0.97 ug | 0.48 ug | 2X MORE if decrease | | Lead | 1.48 ug | 0.78 ug | 2X MORE if decrease | | Magnesium | 10.6 ug | 34.5 ug | 3.5X LESS if increase | | Zinc | 0.24 ug | 5.77 ug | 24X LESS if increase | Pages listed in BOTH the categories Headache and Magnesium {category}

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BACKGROUND AND OBJECTIVES:

Vitamin D deficiency and insufficiency are related with many neurological diseases such as migraine. The aim of this study was to investigate whether pediatric migraine is associated with vitamin D deficiency and the effect of vitamin D therapy on the frequency, duration, severity of migraine attacks, and Pediatric Migraine Disability Assessment (PedMIDAS).

MATERIALS AND METHODS:

We retrospectively examined the patients' levels of calcium, phosphorus, parathyroid hormone, alkaline phosphatase, and 25-OH vitamin D of 92 pediatric migraine patients. The patients were divided into two groups: Group 1, which had low vitamin D levels and received vitamin D therapy, and group 2, which had normal vitamin D levels and did not receive vitamin D therapy. Migraine severity measured by the visual analog scale (VAS), migraine frequency, and duration as well as scores on the PedMIDAS questionnaire were compared with regard to the 25-OH vitamin D levels. In addition, pre- and posttreatment pedMIDAS scores, VAS, migraine frequency, and duration were compared with baseline values.

RESULTS:

A total of 34.7% patients had vitamin D insufficiency (vitamin D levels between 10 and 20 ng/mL), whereas 10.8% had vitamin D deficiency (vitamin D levels < 10 ng/mL). Migraine frequency, migraine duration, and PedMIDAS scores were significantly higher in the group 1 than group 2 (p = 0.004, p = 0.008, and p = 0.001). After vitamin D therapy at sixth months of supplementation, migraine duration was reported statistically significant shorter (p < 0.001) and the migraine frequency, VAS scores, and pedMIDAS scores were statistically significant lower compared with baseline values in group 1 (p < 0.001).

CONCLUSION:

We found a marked correlation between pediatric migraine and vitamin D levels. Vitamin D therapy was beneficial in migraine pediatric patients.

Tags: Headache Intervention Youth