Less able to understand language at age 2 if low vitamin D during second trimester

Created September 2016

Gestational Vitamin 25(OH)D Status as a Risk Factor for Receptive Language Development: A 24-Month, Longitudinal, Observational Study.

Nutrients. 2015 Dec 2;7(12):9918-30. doi: 10.3390/nu7125499.

Tylavsky FA1,2, Kocak M3, Murphy LE4,5, Graff JC6,7, Palmer FB8,9, Völgyi E10,11, Diaz-Thomas AM12, Ferry RJ Jr13,14.

Receptive Language = understand language Ensure a healthy pregnancy and infant with as little as $20 of Vitamin D More vitamin D during pregnancy made for higher mental scores at 14 months – Dec 2012 Healthy pregnancies need lots of vitamin D has the following summary {include}

40 nanogram increased vitamin D ==> Increase Receptive Language score by 1

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Many variables increase Receptive Language score by at least 1

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Emerging data suggest that vitamin D status during childhood and adolescence can affect neurocognitive development. The purpose of this study was to investigate whether gestational 25(OH)D status is associated with early childhood cognitive and receptive language development. The Conditions Affecting Neurocognitive Development and Learning in Early Childhood Study (CANDLE) study enrolled 1503 mother-child dyads during the second trimester of healthy singleton pregnancies from Shelby County TN. Among 1020 participants of the total CANDLE cohort for whom 25(OH)D levels were available, mean gestational 25(OH)D level during the second trimester was 22.3 ng/mL (range 5.9-68.4), with 41.7% of values <20 ng/dL.

Cognitive and language scaled scores increased in a stair-step manner as gestational 25(OH)D levels in the second trimester rose from <20 ng/dL, through 20-29.99 ng/dL, to =30 ng/dL. When controlling for socioeconomic status, race, use of tobacco products, gestational age of the child at birth, and age at the 2-year assessment, the gestational 25(OH)D was positively related to receptive language development (p < 0.017), but not cognitive or expressive language.

Tags: Infant-Child