Lean body mass increased in those getting just 420 IU of vitamin D daily– RCT

Created December 2019

Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults: A Double-Blind, Randomized Controlled Trial.

Ann Nutr Metab. 2019 Dec 4:1-7. doi: 10.1159/000504873

Sun X1,2, Tanisawa K3, Zhang Y4, Ito T3, Oshima S3, Higuchi M3, Cao ZB5.

Raised average Vitamin D levels by 11 ng/mL (47 in group) Lean body mass increased 1 % (43.9 ==> 44.3) in 1 year Placebo group DECREASED lean body mass Doubtless would have had more than 1% increase in LBM if had used higher dose of Vitamin D – say 4,000 IU * Seniors gained 0.3 kg of muscle in 6 weeks with 800 IU and Leucine protein – Aug 2017 * 800 IU ==> 0.3 kg vs 400 IU ==> 0.4 kg in the study on this page * Vitamin D supplementation increases strength of lower muscles – Meta-analysis April 2019 --- 1. Overview Sports and vitamin D has the following summary {include} 1. Sports category starts with {include}

INTRODUCTION:

This study aimed to clarify whether 1 year of vitamin D3 supplementation has a direct effect on body composition and physical fitness in healthy adults.

METHODS:

Ninety-five participants randomly received either 420 IU vitamin D3 per day (n = 48) or placebo (n = 47) in a double-blind manner for 1 year. Lean body mass and percentage body fat were determined. Physical fitness including hand grip strength, leg extension power and cardiorespiratory fitness (CRF) were assessed. Serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]2D) concentrations were assessed using ELISA kits.

RESULTS:

Serum 25(OH)D and (1,25[OH]2D) concentrations significantly increased by approximately 11.2 ± 9.2 ng/mL (pinteraction <0.001)and 7.0 ± 7.8 pg/mL (pinteraction <0.001) after 1 year of vitamin D3 supplementation respectively.

Lean body mass significantly increased from 43.8 ± 9.6 to 44.3 ± 9.8 kg in vitamin D group, while no change was observed in placebo group (from 42.6 ± 8.9 to 42.4± 8.9 kg) after 1 year intervention. Furthermore, no treatment effects on other indicators of body composition and physical fitness were observed.

CONCLUSIONS:

One year of vitamin D supplementation effectively improves lean body mass, but not muscle strength and CRF in healthy adults.

Tags: Sports