How cancer is fought by Vitamin D (Ovarian this time)

Created February 2020

Vitamin D and Ovarian Cancer: Systematic Review of the Literature with a Focus on Molecular Mechanisms

Cells 2020, 9(2), 335; https://doi.org/10.3390/cells9020335

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by Andraž Dovnik 1,* andNina Fokter Dovnik 2

1 University Clinic for Gynaecology and Obstetrics, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia

2 Department of Oncology, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia

Vitamin D is a lipid soluble vitamin involved primarily in calcium metabolism. Epidemiologic evidence indicates that lower circulating vitamin D levels are associated with a higher risk of ovarian cancer and that vitamin D supplementation is associated with decreased cancer mortality. A vast amount of research exists on the possible molecular mechanisms through which vitamin D affects cancer cell proliferation, cancer progression, angiogenesis, and inflammation. We conducted a systematic review of the literature on the effects of vitamin D on ovarian cancer cell.

Tags: Ovarian Cancer Vit D Receptor