Dosing error gave 12000 IU daily vitamin D to infant, but no indication of any problem

Dosing Error With Over-the-Counter Vitamin D Supplement: A Risk for Vitamin D Toxicity in Infants.

Clin Pediatr (Phila). 2012 Apr 5.

Rajakumar K, Reis EC, Holick MF.

Instead of 400 IU an infant was given 12,000 IU of vitamin D daily for 20 days

Due to parents giving 1 mil liter as they were used to instead of 1 drop, from the new product

Authors were extremely concerned about infant toxicity

However, no problems at all:

Small excerpt from the paper

^The infant was clinically stable with no symptoms and was feeding and acting well.

The infant had no history of irritability, constipation, or abnormal movements. Examination revealed a calm, alert, well-appearing infant (weight 5.6 kg; 3rd-15th World Health Organization percentile) with no focal findings except slightly increased patellar deep tendon reflexes; no clonus was present. Serum calcium (10.5 mg/dL, reference range 8.8-10.8 mg/dL), phosphorus (6.4 mg/dL, reference range 4.5-6.5 mg/dL), electrolyte panel, creatinine, and blood urea nitrogen were normal.^

20 days at 12,000 IU per day = 240,000 IU

Blood level was 400 ng/ml, which dropped down naturally to 50ng in 4 months

There continues to be is so much fear from vitamin D toxicity – even with decades of experience around the world with very young humans and other mammals with very high levels of vitamin D

📄 Download the PDF from VitaminDWiki

See also VitaminDWiki

• High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis April 2022

• Infants in Finland who got 2000 IU vitamin D daily grew to normal height – March 2011

• Rare infant vitamin D toxicity – due to errors which resulted in more that 240,000 IU – Jan 2014

• 600,000 IU of vitamin D2 given to infants every 4 months for decades in East Germany

• Lambs get 10X more vitamin D3 in their milk formula than humans = 2,000 IU per pint of milk

• All items in category Infant-Child and Vitamin D items

• Overview Toxicity of vitamin D which has the following graph for adults

Many weeks for a really large DAILY dose of vitamin D to become toxic for adults

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