Eur J Clin Nutr. 2011 Jul 6. doi: 10.1038/ejcn.2011.106.
Soares MJ, Chan She Ping-Delfos W, Ghanbari MH.
Program of Nutrition, School of Public Health, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia, Australia.
Obesity often coexists with low calcium intake and vitamin D insufficiency. There is emerging evidence of a role for these nutrients in the regulation of body weight. However, it is unclear whether increasing intakes of calcium and/or vitamin D during energy restriction, is a better strategy for weight and fat loss. We searched the literature from 2000 to date for randomized controlled trials (RCTs) on weight loss that had increased calcium or vitamin D per se, or in combination. Primary and secondary studies were included for this analysis.
A total of 15 RCTs on calcium with or without vitamin D and seven on vitamin D alone met our criteria.
Two studies reported that supplemental calcium significantly increased fat loss during caloric restriction by 1.8 and 2.2?kg, three found differences between 1 and 3.5?kg but were statistically nonsignificant, while nine trials were equivocal (±0.7?kg). The data on vitamin D supplementation during weight loss were too few to make firm conclusions. Current evidence from RCTs did not consistently support the contention that calcium and vitamin D accelerated weight or fat loss in obesity. There were studies that favoured the hypothesis but lacked the statistical power. There is a need for RCTs to examine the influence of vitamin D on body fat.European Journal of Clinical Nutrition advance
online publication, 6 July 2011; doi:10.1038/ejcn.2011.106.
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