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Tanning potential predicts risk of Prostate Cancer in Blacks – Nov 2014

Use of Tanning Potential as a Predictor for Prostate Cancer Risk in African-American Men.

In Vivo. 2014 11-12;28(6):1181-1187.
Beyene D1, Daremipouran M1, Apprey V2, Williams R3, Ricks-Santi L4, Kassim OO5, Naab TJ6, Kanaan YM7, Copeland RL Jr8.
1Howard University Cancer Center, College of Medicine, Howard University, Washington, DC, U.S.A.
2National Human Genome Center, College of Medicine, Howard University, Washington, DC, U.S.A. Community and Family Medicine, College of Medicine, Howard University, Washington, DC, U.S.A.
3Department of Family Medicine, Howard University Hospital, Washington, DC, U.S.A.
4Cancer Research Center, Hampton University, Hampton, VA, U.S.A.
5Department of Microbiology, College of Medicine, Howard University, Washington, DC, U.S.A.
6Department of Pathology, Howard University Hospital, Washington, DC, U.S.A.
7Howard University Cancer Center, College of Medicine, Howard University, Washington, DC, U.S.A. Department of Microbiology, College of Medicine, Howard University, Washington, DC, U.S.A.
8Howard University Cancer Center, College of Medicine, Howard University, Washington, DC, U.S.A. Department of Pharmacology, College of Medicine, Howard University, Washington, DC, U.S.A. rlcopeland at howard.edu.

Background/Aim: Vitamin D deficiency in African-Americans is common due to the high melanin content of the skin that reduces the absorption of UV radiation. To determine if there is a correlation between UV exposure, tanning potential and vitamin D with prostate cancer (PC) risk, we conducted a case-control study of 183 African-American men aged 40 years and older residing in the Washington, DC area.

Patients and Methods: PC status was described as a binary variable as the presence or absence of cancer and the environmental factors as continuous variables. We used a logistic regression model describing PC as the response, while age, tanning potential, sunlight and vitamin D were treated as the predictors.

Results: Men aged 60 years and older had a seven-fold increased risk for developing PC compared to those aged 50 years and less (p<0.003).
Tanning potential was a significant (p=0.05) risk factor for PC, while sunlight exposure and vitamin D were not.
Tanning potential was also significant (p=0.044) when adjusted for vitamin D and age.
However, tanning potential was only marginally significant when adjusted for sunlight exposure (p=0.064)

Conclusion: The findings of this study indicate that tanning potential may be a predictor for PC risk in African-American men.

Copyright © 2014 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

PMID: 25398820


Was unable to quickly find a definition of "tanning potential"
There is a free 1959 paper on "tanning potential" in JSTOR

See also VitaminDWiki

See also PubMed

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