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Omega-3, Vitamin D, and other nutrients decrease mental health problems – March 2015

From Importance of a balanced diet for mental health Science Daily

Omega-3, essential amino acids, B-group vitamins (B12 and folate), vitamin D and minerals like zinc, magnesium and iron.
A balanced and high-quality diet, such as the Mediterranean, provides all of these, the researchers note.

Jerome Sarris, Alan C Logan, Tasnime N Akbaraly, G Paul Amminger, Vicent Balanzá-Martínez, Marlene P Freeman, Joseph Hibbeln, Yutaka Matsuoka, David Mischoulon, Tetsuya Mizoue, Akiko Nanri, Daisuke Nishi, Drew Ramsey, Julia J Rucklidge, Almudena Sanchez-Villegas, Andrew Scholey, Kuan-Pin Su, Felice N Jacka. Nutritional medicine as mainstream in psychiatry. The Lancet Psychiatry, 2015; 2 (3): 271 DOI:10.1016/S2215-0366(14)00051-0
PDF is free to those who register (quick) at the Lancet site

References include

  • Lai JS, Hiles S, Bisquera A, Hure AJ, McEvoy M, Attia J.
    A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults. Am J Clin Nutr 2014; 99: 181–97. 12
  • Psaltopoulou T, Sergentanis TN, Panagiotakos DB, Sergentanis IN, Kosti R, Scarmeas N.
    Mediterranean diet, stroke, cognitive impairment, and depression: a meta-analysis. Ann Neurol 2013; 74: 580–91.
  • Sánchez-Villegas A, Martínez-González MA, Estruch R, et al.
    Mediterranean dietary pattern and depression: the PREDIMED randomized trial. BMC Med 2013; 11: 208.


Authors are a part of International Society for Nutritional Psychiatry Research (ISNPR)
Which has an interesting set of publications online – with hyperlinks

  • A randomized placebo-controlled trial of an omega-3 fatty acid and vitamins E+C in schizophrenia (Open Access)
  • Dietary Patterns and Depressive Symptoms over Time: Examining the Relationships with Socioeconomic Position, Health Behaviours and Cardiovascular Risk (Open Access)
  • Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry (Open Access)
  • Vitamin-mineral treatment of attention-deficit hyperactivity disorder in adults: double-blind randomised placebo-controlled trial
  • Moving Towards a Population Health Approach to the Common Mental Disorders – (Open Access)
  • Dietary patterns and suicide in Japanese adults: health center-based prospective study
  • Fish Oil for Attenuating Posttraumatic Stress Disorder Symptoms among Rescue Workers after the Great East Japan Earthquake: A Randomized Controlled Trial (Open Access)
  • Dietary patterns and depressive symptoms among Japanese men and women
  • Serum folate and homocysteine and depressive symptoms among Japanese men and women (Open Access)
  • Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population
  • PTSD and the attenuating effects of fish oils: Results of supplementation after the 2011 Great East Japan Earthquake (Open Access)
  • Are omega-3 fatty acids anti-depressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression (Open Access)
  • Long-Chain -3 Fatty Acids for Indicated Prevention of Psychotic Disorders (Open Access)
  • Maternal and Early Postnatal Nutrition and Mental Health of Offspring by Age 5 Years: A Prospective Cohort Study
  • Depression, diet and exercise (Open Access)
  • Preventative strategies in depression: gathering evidence for risk factors and potential interventions (Open Access)
  • Therapeutic use of omega-3 fatty acids in bipolar disorder
  • Association of Western and Traditional Diets With Depression and Anxiety in Women (Open Access)
  • A prospective study of diet quality and mental health in adolescents (Open Access)
  • The association between habitual diet quality and the common mental disorders in community-dwelling adults: The Hordaland Health Study (Open Access)
  • Dietary selenium and major depression
  • Red Meat Consumption and Mood and Anxiety Disorders
  • The dietary intake of fish, PUFAs and clinical depressive and anxiety disorders in population-based women
  • Diet quality and mental health problems in adolescents from East London: a prospective study
  • The association between fruit and vegetable consumption and mental health disorders: evidence from four waves of a national survey of Canadians
  • Nutrients and the common mental disorders
  • A Randomised Controlled Trial Investigating an Annual High Dose Vitamin D3 and Mental Well-Being: Vital D Study (Open Access)
  • Diet quality in bipolar disorder in a population-based sample of women
  • Diet and depressed mood in adolescents: Results from the Healthy Neighbourhoods study
  • The association between magnesium intake and depression and anxiety in community-dwelling adults: The Hordaland Health Study
  • Diet, exercise, lifestyle modification and complementary medicine for anxiety disorders: A review of current evidence (Open Access)
  • A randomised, controlled trial of a dietary intervention for adults with major depression (the SMILES trial): study protocol (Open Access)
  • Broad-spectrum micronutrient formulas for the treatment psychiatric symptoms: A systematic review
  • Shaken but unstirred? Effects of micronutrients on stress and trauma after an earthquake: RCT evidence comparing formulas and doses
  • Omega-3 polyunsaturated fatty acids for major depressive disorder
  • Phospholipase A2 and cyclo-oxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels (Open Access)
  • Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part II – contemporary contextual research (Open Access)
  • Intestinal microbiota, probiotics and mental health: from Metchnikoff to modern advances: Part III – convergence toward clinical trials (Open Access)
  • Clinical implications of lipid peroxidation in acne vulgaris: old wine in new bottles
  • Omega-3 Fatty Acid Supplementation in Adolescents With Borderline Personality Disorder and Ultra-High Risk Criteria for Psychosis: A Post Hoc Subgroup Analysis of a Double-Blind, Randomized Controlled Trial
  • Polyunsaturated fatty acids in emerging psychosis
  • Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seeking ultra-high-risk individuals
  • Omega-3 fatty acid supplementation changes intracellular phospholipase A2 activity and membrane fatty acid profiles in individuals at ultra-high risk for psychosis
  • Dietary intake of folate, other B vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults
  • Serum pyridoxal concentrations and depressive symptoms among Japanese adults: results from a prospective study
  • Fish consumption and cardiovascular response during mental stress (Open Access)
  • Potential role of brain-derived neurotrophic factor in omega-3 fatty acid supplementation to prevent posttraumatic distress after accidental injury: An open-label pilot study (Open Access)
  • Clearance of fear memory from the hippocampus through neurogenesis by omega-3 fatty acids: A novel preventive strategy for posttraumatic stress disorder? (Open Access)
  • Association between serum 25-hydroxyvitamin D and depressive symptoms in Japanese: analysis by survey season

See also VitaminDWiki

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