- Update on the role of vitamin D in the prevention of osteoporosis
- VitaminDWiki - Overview Osteoporosis and vitamin D contains
- VitaminDWiki - Osteoporosis category contains
- VitaminDWiki - Falls and Fractures category contains
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Update on the role of vitamin D in the prevention of osteoporosis
Vitamin D - Updates 2022;5(1):4-7. https://doi.org/10.30455/2611-2876-2022-1e
Stefano Berardi, Francesco Paolo Cantatore
Rheumatology Clinic, Department of Medical and Surgical Sciences, University of FoggiaPackages of Vitamin D for Italian Women
In recent years the possible multiple positive effects of vitamin D (antineoplastic, cardioprotective, immunomodulatory, etc.) have aroused growing interest and an increase in scientific (and non-scientific) publications on the subject. However, uncertainties about its usefulness in the prevention of osteoporosis have also been raised, following discordant results in the literature, beyond any reasonable doubt on extra-skeletal effects. Osteoporosis has a burdensome impact on the healthcare system: in Italy approximately 3.5 million women and 1 million men are affected by the disease. Incidence increases with age (the steady ageing of the population leads to more cases). From age 50, the incidence of fragility fractures increases progressively, becoming comparable to that of stroke and breast cancer 1. Annual costs attributable to such fractures (acute management and longterm disability) grow with the ageing of the population. What is needed is an acceptable prevention strategy that makes the best use of available resources. Download the PDF from VitaminDWiki
They recommend 30-40 ng
VitaminDWiki - Overview Osteoporosis and vitamin D contains
- FACT: Bones need Calcium (this has been known for a very long time)
- FACT: Vitamin D improves Calcium bioavailability (3X ?)
- FACT: Should not take > 750 mg of Calcium if taking lots of vitamin D (Calcium becomes too bio-available)
- FACT: Adding vitamin D via Sun, UV, or supplements increased vitamin D in the blood
- FACT: Vitamin D supplements are very low cost
- FACT: Many trials, studies. reviews, and meta-analysis agree: adding vitamin D reduces osteoporosis
- FACT: Toxic level of vitamin D is about 4X higher than the amount needed to reduce osteoporosis
- FACT: Co-factors help build bones.
- FACT: Vitamin D Receptor can restrict Vitamin D from getting to many tissues, such as bones
- It appears that to TREAT Osteoporosis:
- Calcium OR vitamin D is ok
- Calcium + vitamin D is good
- Calcium + vitamin D + other co-factors is great
- Low-cost Vitamin D Receptor activators sometimes may be helpful
- CONCLUSION: To PREVENT many diseases, including Osteoporosis, as well as TREAT Osteoporosis
- Category Osteoporosis has
221 items - Category Bone Health has
314 items Note: Osteoporosis causes bones to become fragile and prone to fracture
Osteoarthritis is a disease where damage occurs to the joints at the end of the bones
VitaminDWiki - Osteoporosis category contains
221 items in category - see also Overview Osteoporosis and vitamin D - Overview Fractures and vitamin D
- Bone - Health
314 items - VitaminDWiki pages with BONE MINERAL DENSITY or BMD in title 29+ pages
- Search VitaminDWiki for OSTEOPENIA 1740 items as of July 2020
13 articles are in both Osteroporosis and Vitamin D Receptor categories 10 articles are in both Osteroporosis and Meta-analysis categories - 20X increase in vitamin D sold and 36 percent decrease in osteoporosis business in Australia – Nov 2013
VitaminDWiki - Falls and Fractures category contains
258 items in FALLS and FRACTURES - Vitamin D and Calcium cost-effectively reduce falls and fractures – April 2019
- see also Overview Seniors and Vitamin D
Falls
- Fall prevention - Vitamin D is one of the ways - umbrella review Jan 2024
- Deaths due to falls doubled in just a decade (age-adjusted, perhaps decreased vitamin D) – June 2019
- Preventing Falls in Older Adults – Vitamin D combination is the best - JAMA Meta-analysis Nov 2017
- Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
- Falls reduced by a third if achieved 40 ng level vitamin D– RCT Sept 2018
- Note: It took 6 months to get to that level. Most trials last only 3 months
- Vitamin D prevents falls – majority of meta-analyses conclude – meta-meta analysis Feb 2015
- Falls reduced by Vitamin D: 13 percent reduction if more than 700 IU – review of 38 trials – Aug 2022
Left hand column section as of Nov 2024
Ankle (16+)Bone Mineral Density (28+)Children (16+)Hip Fractures (68+)Vertigo (22+)Fracture
- Hip fractures are predicted by 10 factors – low Vitamin D is the biggest – Aug 2023
- Vitamin D and fractures – 24 meta-analyses and counting – Dec 2014
- Low trauma bone fractures in seniors – considering Vitamin D loading dose for all, without testing – Nov 2019
- Vitamin K (any amount and any kind) reduced bone fractures by 24 percent – meta-analysis – May 2019
- 77+ Hip fracture items in VitaminDWiki title Click here for details examples:
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4649 visits to this page Italian women taking Vitamin D (Osteoporosis, etc) - Dec 20222689 visitors, last modified 06 Mar, 2024, This page is in the following categories (# of items in each category)Attached files
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- Category Bone Health has
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