Vitamin D supplementation, moderate sun exposure, and control of immune Diseases.
Department of Inflammation, Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia 6008, Australia.
Discov Med. 2012 Jun;13(73):397-404.
There is considerable debate about the benefits of vitamin D supplementation for multiple sclerosis, allergic asthma, and type 1 diabetes.
This has been driven mainly by observational studies linking vitamin D deficiency and insufficiency with increased prevalence of autoimmune and other diseases driven by immune processes.
Randomized controlled trials of vitamin D supplementation to treat these (and other) diseases have been disappointing.
This review examines the evidence that circulating vitamin D levels provide a surrogate measure of sun exposure and that it is the other molecules and pathways induced by sun exposure, rather than vitamin D-driven processes, that explain many of the benefits often attributed to vitamin D.
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See also VitaminDWiki
- Less intestinal cancer in mice if add vitamin D, but even less with ultraviolet light – June 2014
- Solar UVB reduces Cancer Risk – Grant, Jan 2013
- Beneficial effects of UV radiation other than via vitamin D production – June 2012
- There is more in UV than vitamin D which suppresses MS in mice – April 2010
- Lack of UV 20X more associated with MS than any other variable – Dec 2010
- UV produces more than vitamin D – Aug 2011
- Opinion: sun better than UV better than vitamin D
- 5 Amazing Properties of Sunlight You've Never Heard About
- Nitric oxide (from Sun, UVA, Vitamin D) reduces cardiovascular problems
- Benefits of sun are more than vitamin D – 2008
- UV decreases Multiple Sclerosis via cis-urocanic acid (and via vitamin D) – June 2013