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COVID-19 Coronavirus can most likely be fought by Vitamin D


COVID-19 News highlights

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  • 300,000 US deaths for ANY virus having an infection rate of 5% and a fatality rate of j2% New York Times March 16
    • Has an interactive slider bar - note: MAX Fatality rate = 3% (but some estimates put COVID-19 fatality rate at >10%)
  • UK held a half-marathon for 6,200 joggers BBC March 16
    • Probably the worse possible gathering of people in a pandemic: People breathing heavily, close together.
    • Appears that UK has 10+ half-marathons scheduled for March
  • Everything You Need to Know About Coronavirus Testing Wired March 16
    • “We know now, just the fact of community spread says that at least 1 percent, at the very least 1 percent, of our population is carrying this virus in Ohio today"
    • WHO keeps track of the scores of different PCR protocols to test for COVID-19 in 120 countries - CDC developed 1 of the many protocols
    • Protocols cover how RNA is removed,which reagents, how many temperature cycles, readout mechanism. Food Analgy: Similar ingredients, but different recipes
    • US law did not permit US groups to use any other of the protocol used elsewhere around the world - until Feb 29
    • "At least 20 companies have announced plans to develop “molecular point-of-care” tests, basically all-in-one, mostly automated systems that a frontline health care worker can use to get results in a half hour,"
    • Nothing about accuracy: False Positives nor False Netagives
  • 58,000 US schools closed The Atlantic March 16
    • "... closing schools reduces the total number of cases in the community by about 25 percent and postpones the peak of the pandemic by a week or two, which is helpful."" has links to 3 studies
  • A Sunday without Church New York Times March 15
    • "When it was time to take communion, the pastor, Dr. David Anderson, urged people (via Facebook Live) to use whatever they had in their kitchens. “Not Corona,” he joked. Some used Ritz crackers and water, others cranberry juice or coffee."
  • First two Emergency Room Doctors Are in Critical Condition With Coronavirus Ney York Times March 14
    • “As compared to anyone else at a hospital, you (ICU staff) are operating with the most incomplete information,”
  • Puerto Rico Imposes Curfew, Shuts Businesses Over Coronavirus Ney Work Times March 15
    • " two-week closure for the majority of businesses on the island, and a 9 p.m. overnight curfew through March 30."
    • "The only exceptions to the closure orders are supermarkets; restaurants offering carryout or delivery; pharmacies; medical equipment stores; gas stations and banks, along with suppliers to those businesses."
  • Countries with more Acute Care beds appear to have slower COVID-19 growth rates Niskanen Center  see also Wikipedia

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WHO: What China did right can aid others

  • Interview of same W.H.O. expert who visited China New York Times March 4 2020
    • CT scans in < 10 minutes (US use older CT machines which often take > 60 minutes)
    • If CT scan shows the possibility of COVID-19 then a PCR test is made
    • - person is not permitted to leave until results are ready in 4 hours
    • Typical Chinese hospital has 50 ventilators and 5 extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail. - far more than a typical hospital in the US or Europe
  • China’s cases of Covid-19 are finally declining. A WHO expert explains why. VOX March 2
    • Free tests and Free treatment for everyone reduced barriers (In US a few people without insurance paid >$3,000 - and they were not infected)
    • Get fast test results (4-7 hours) and track/quarantine all contact within quickly (historically in the US the test results were no available for 4 days)
    • Some lungs were so inflamed that they oxygenated the blood outside of the body - far fewer deaths than when only using ventilators
    • Repurposed entire sections of hospitals for COVID-19 - substantially reducing non-emergency hospital use
    • Decided to not test until the person had symptoms, and even then only a fraction with symptoms had COVID-19
    •  Download the W.H.O. 40 page report from VitaminDWiki

Vitamin D

Why/How Vitamin D both treats and prevents Coronavirus

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VitaminDWiki - relevant studies

Virus category in VitaminDWiki


15 most-recently changed items in Virus Category

Id Page Hits Last modification Creator Categories
11580 COVID-19 Coronavirus can most likely be fought by Vitamin D 187147
08 Apr, 2020 01:01
admin Virus
11720 Vitamins C and D being considered as Coronavirus Treatments - April 7, 2020 22
07 Apr, 2020 21:08
admin Virus
11717 Vitamin D may be a COVID-19 Game-changer - BMJ April 6, 2020 71
07 Apr, 2020 17:46
admin Virus
11716 Global Push for RCTs in COVID-19 - April 4, 2020 62
07 Apr, 2020 02:19
admin Virus
11715 Immunity against infection: letter sent to the editor of The Times UK - April 6, 2020 114
06 Apr, 2020 19:02
admin Virus
11712 COVID-19 is strongly associated with low vitamin D 366
05 Apr, 2020 16:44
admin Virus
11711 Viral infection wheezing 24X more likely if less than 15 ng of Vitamin D – Dec 2019 116
04 Apr, 2020 14:05
admin Breathing
Virus
6630 Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015 10398
04 Apr, 2020 08:44
admin Intervention
Vitamin D in Canada
Virus
11709 Vitamin D should prevent COVID-19 (recommended dose takes 3 months to raise levels) - April 2020 358
03 Apr, 2020 21:05
admin Virus
11710 Indictions of increase COVID-19 problems if dark skin in the UK- April 3 2020 114
03 Apr, 2020 19:48
admin Skin - Dark
Virus
7499 Virus 16233
03 Apr, 2020 15:38
admin Category
Virus
10063 Vitamin D probably can both prevent Influenza and augment vaccine prevention – Aug 2018 1343
02 Apr, 2020 23:29
admin Virus
11707 Preventing a COVID-19 pandemic with Vitamin D – Grant April 2020 378
02 Apr, 2020 12:24
admin Virus
11684 Quercetin and Vitamin D —possible Allies Against Coronavirus - March 2020 1740
02 Apr, 2020 02:51
admin Vitamin D Receptor
Virus
11218 Infections and low vitamin D (including deep neck infections) 1075
01 Apr, 2020 18:30
admin Immunity
Inflammation
Virus

Coronaviruses less able to attach to cells if have enough Vitamin D

Coronaviruses attach to cells via ACE2, Vitamin D might reduce ACE2 starts with the following

Fact All Coronavirus attach to ACE2 enzyme in human cells
Suspected Vitamin D reduces ACE2 enzyme
Fact All previous human Coronavirus are fought by Vitamin D
Hypothesis Vitamin D will also fight the new form of Coronavirus, COVID-19

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VitaminDWiki tried in early Feb to get Vitamin D to China

VitaminDWiki sent 50 emails to Vitamin D researchers in China Feb 5 - received only a single reply
The email suggested that 300,000 IU of vitamin D be given to 100 hospital patients and look for improved recovery in <5 days
Vitamin D could be bought locally or sent for free by VitaminDWiki
Next - VitaminDWiki is considering a similar email letter to vitamin D researchers in South Korea, where there is a lot of COVID-19 anxiety
   Note S. Koreans are 50X more likely to take supplements (such as vitamin D) than Chinese

Vitamin D can be augmented by any of the following

  • Vitamin C, Quercetin, Zinc, – each of which improves immune systems
  • UV-C air purification – which reduces infection of others in the room and re-infection
    • Note UV-C disrupts the virus RNA, such that it cannot become active again
  • Inhaled Vitamin D – likely to provide prevention, it might provide treatment
  • room humidifier with possible vitamin D emulsion - likely prevention, unknown treatment
  • Vitamin D cream – faster than oral Vitamin D, gut-friendly, and no pills to swallow, but is 10X more expensive
  • Acivators of the Vitamin D Receptor (resveratrol, etc) - which increase vitamin D actually getting to cells

Coronavirus Symptoms
some will do better with a gut-friendly form of Vitamin D

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Image from USA Today - from CDC information
Primarily the Coronavirus infects in the lungs, but sometimes also infects the gut (both humans and animals)

Gut-Friendly forms of Vitamin D include emulsions, topical, and water soluable
Patients with gut issues will probably respond better to gut-friendly forms of Vitamin D
Oil-based vitamin D is the least gut-friendly

(1) Coronavirus ==> (2) Pneumonia ==> (3) ARDS ==> (4) Sepsis
- all associated with low vitamin D and all are treated by Vitamin D

(1) this page
(2) Pneumonia Risk, intensity, and mortality all associated with low vitamin D
(3) Acute respiratory distress – 100 percent of patients were vitamin D deficient– April 2015
(4) Vitamin D reduces sepsis


Other Sources of information

Archive of preprints for Medical Studies (which have NOT been peer-reviewed) - 616 on Coronavirus March 19
Includes Cases - Deaths - Countries - Death Rate - Transmission Rate - Incubation - Age - Symptoms -PDFs and comments by readers via Twitter, etc
A few interesting preprints from March 18-20
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Real-time sources of Coronavius statistics, maps.etc.

*Many strains of COVID-19 are spreading around the world - animated map - 8 strains so far

    • Wonder if a single vaccine can prevent many strains.

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CLICK HERE to see the latest Johns Hopkins University integration of data from around the world
Takes about 20 seconds for the image to be completed
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Snapshot of March 9, 2020
JHU posts all of the data, day by day, in Google Sheets

WHO has a similar map perhaps based on the same data
- - - - - - -
Animated map showing spread around the world Snapshot March 9
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Map includes trends for each Country, state level details for US
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Bing March 16
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New York Times March 22
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- - - - - - - - - - - - - - - - - - - - - - -
See map of infection at each day in the past
Basically provides a slider-bar on the Google sheet data (above)
Also allows overlaying SARS, Swine flu, and Ebola outbreaks on the same map
- - - - - - - - - - - - - - - - - - - - - - -
Coronavirus at World Meter
- - -
W.H.O. tracking COVID-19 in Europe
Snapshots as of Feb 26
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Wikipedia has many excellent Coronavirus entries - most have real-time maps

France   Australia   US  Italy   italy real time map   Testing Europe  Japan  Asia   Singapore    Spain    S. Korea   Germany   Canada    UK   Chile   Iran    Brazil    Russia  india
2019–20 Wuhan coronavirus outbreak

  • "The first person known to have fallen ill due to the new virus was in Wuhan on 1 December 2019.
    A public notice on the outbreak was released 30 days later by Wuhan health authority on 31 December 2019;"
  • "On 6 February, the Chinese National Health Commission started to change how cases were reported – asymptomatic carriers, who tested positive for the virus but did not show clinical symptoms, would no longer be included in the number of confirmed cases. This had the effect of reducing the total number of cases reported, but also meant that potentially contagious individuals were ignored in reports."
  • "On 12 February, the Hubei government adopted a broader definition of confirmed cases, which now includes clinically diagnosed patients diagnosed by their symptoms and CT scans but without nucleic acid test, which can take days to process and delay treatment."
    • Constantly updated global map is online - snapshot as of Feb 14
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2019-nCoV acute respiratory disease
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2020 Hubei lockdowns includes travel restrictions etc outside of China
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Evacuations related to the 2019–20 Wuhan coronavirus outbreak
Misinformation related to the 2019–20 Wuhan coronavirus outbreak


Coronavirus still viable on surfaces 4 days later (as long as 9 days at room temperature)

Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents - Jan 2020
Overview of 22 Coronavirus studies no data on the effectivity of handwashing
 Download the PDF via Sci-Hub from VitaminDWiki
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Humans: SARS-CoV, and MERS-CoV
Animals: transmissible gastroenteritis virus (TGEV), mouse hepatitis virus (MHV) and canine coronavirus (CCV)

Update - Preprint: Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1 March 10, 2020
Overall, stability is very similar between HCoV-19 and SARS-CoV-1.
We found that viable virus could be detected in

  • aerosols up to 3 hours post aerosolization, up to
  • 4 hours on copper, up to
  • 24 hours on cardboard and up to
  • 2-3 days on plastic and stainless steel.

HCoV-19 and SARS-CoV-1 exhibited similar half-lives in aerosols, with median estimates around 2.7 hours. Both viruses show relatively long viability on stainless steel and polypropylene compared to copper or cardboard: the median half-life estimate for HCoV-19 is around 13 hours on steel and around 16 hours on polypropylene. Our results indicate that aerosol and fomite transmission of HCoV-19 is plausible, as the virus can remain viable in aerosols for multiple hours and on surfaces up to days.


Clinical Trials

19 C0VID-19 Clinical trials register in the US started in China - Feb 2020


539 Clinical trials for COVID-19 in CHINA as of April 6 - including one monitoring outcome vs Vitamin D


Short URL = is.gd/CoronaD

Title revision of Feb 2020 caused the visitor count to reset.
There have actually been 187147 visitors to this page since it was originally made




Created by admin. Last Modification: Wednesday April 8, 2020 01:01:45 GMT-0000 by admin. (Version 583)

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