Short gap between pregnancies tied to higher autism risk? HealthDay News
- Recommended at least 2 years
- “study author Dr. Agustin Conde-Agudelo. He is a researcher at the World Health Organization Collaborating Center in Human Reproduction at the University of Valle in Cali, Colombia.”
- “The study was published online April 7 and in the May print issue of the journal Pediatrics.”
Article does not say how much increase
Study probably does, but was not online as of April 8, 2016
Inter-Pregnancy Intervals and the Risk of Autism Spectrum Disorder: Results of a Population-Based Study.
J Autism Dev Disord. 2015 Jul;45(7):2056-66. doi: 10.1007/s10803-015-2368-y.
Durkin MS1, DuBois LA, Maenner MJ.
1Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, 789 WARF, 610 Walnut Street, Madison, WI, 53726, USA, mdurkin at wisc.edu.
Recent studies have reported an increased risk of autism among second-born children conceived <12 versus >36 months after the birth of a sibling. Confirmation of this finding would point to inter-pregnancy interval (IPI) as a potentially modifiable risk factor for autism. This study evaluated the relationship between IPI and autism spectrum disorder (ASD) risk in a Wisconsin birth cohort of 31,467 second-born children, of whom 160 resided in the study area and were found to have ASD at age 8 years. In adjusted analyses, both short (<12) and long (>84 month) IPIs were associated with a two-fold risk of ASD relative to IPIs of 24-47 months (p < 0.05). The long IPI association was partially confounded by history of previous pregnancy loss.
PMID: 25636677 available at DeepDive
- Autism is associated with low vitamin D – meta-analysis Oct 2015
- Most Autism Risk factors are associated with low vitamin D - March 2014
- Increase early births by 40 percent if less than 6 months to restock vitamin D – Feb 2011
Note: early birth is probably due to vitamin D levels not yeat restocked
Healthy pregnancies need lots of vitamin D has the following summary
|0. Chance of not conceiving||3.4 times||Observe|
|1. Miscarriage||2.5 times||Observe|
|2. Pre-eclampsia||3.6 times||RCT|
|3. Gestational Diabetes||3 times||RCT|
|4. Good 2nd trimester sleep quality||3.5 times||Observe|
|5. Premature birth||2 times||RCT|
|6. C-section - unplanned||1.6 times||Observe|
|Stillbirth - OMEGA-3||4 times||RCT - Omega-3|
|7. Depression AFTER pregnancy||1.4 times||RCT|
|8. Small for Gestational Age||1.6 times||meta-analysis|
|9. Infant height, weight, head size |
within normal limits
|10. Childhood Wheezing||1.3 times||RCT|
|11. Additional child is Autistic||4 times||Intervention|
|12.Young adult Multiple Sclerosis||1.9 times||Observe|
|13. Preeclampsia in young adult||3.5 times||RCT|
|14. Good motor skills @ age 3||1.4 times||Observe|
|15. Childhood Mite allergy||5 times||RCT|
|16. Childhood Respiratory Tract visits||2.5 times||RCT|
RCT = Randomized Controlled Trial