Blood omega-3 fatty acids and death from COVID-19: A Pilot Study
medRxiv preprint doi: https://doi.org/10.1101/2021.01.06.21249354;
4% death rate if Omega-3 index >5.7
17% death rate if Omega-3 index <5.7
Comments by VitaminDWiki
- A company making Omega-3 Index tests and products is in the same city as 2 of the authors
- Good Omega-3 indexes have been associated with many forms of good health
- especially low levels of inflammation
- Increasing the Omega-3 intake increases Omega-3 index in a few months
- Sometimes the Omega-6 intake must also be reduced
- Note: The Omega-3 index is a ratio of Omega-3 to Omega-6
- Omega-3 is far more expensive than Vitamin D, which also decreases COVID-19 deaths
- For many health problems, Omega-3 and Vitamin D work synergistically
- It is anticipated that the combination will be synergistic with COVID-19 as well
- Vitamin D and Omega-3 category listing has
410 items along with related searches - Clinical trials for Omega-3 and COVID19 #1, #2 #3 Omega-3 nasal spray as of Jan 12 2021
- Items in both categories Virus and Omega-3 are listed here:
- How vitamins A, B, C, D, E, F (Omega), K fight COVID - Feb 2022
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript - Dec 2021
- COVID-19 decreased risk if add Vitamin D, A, C, NAC, Se, Zn, or Omega-3 – Dec 2021
- High-dose Omega-3 fought COVID in 2 hospital trials (6x reduction in ICU, reduced time) – Masterjohn Oct 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- Omega-3 reduces risk of COVID-19 - many studies
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 etc. – June 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- COVID-19 ICU survival rate increased 7X by daily Omega-3 – RCT March 2021
- 4X fewer COVID-19 deaths in those having high Omega-3 index – Jan 6, 2021
Magnesium
- Magnesium, similar to Omega-3, is synergistic with Vitamin D and may also help fight COVID-19
- Vitamin D and Magnesium category listing has
62 items along with related searches - Items in both categories Virus and Magnesium are listed here:
- Long-COVID 3.1 X more likely if insufficient amounts of Magnesium and Vitamin D – March 2024
- COVID appears to be treated by many antioxidants (Vitamins D, C, E, K, and Quercetin, Curcumin, etc) – Jan 2023
- Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022
- Low Magnesium associated with severe COVID – many studies
- COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021
- COVID treatment patent applied for - using Rutin, Vitamin D, Vitamin C, Magnesium, etc. – April 2022
- COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
- Hypothesis: 2 long-haul COVIDs: had mild symptoms and had needed ICU - April 2022
- Excess Magnesium is bad for health (COVID hospital days in this case) – April 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- Long Covid, Short Magnesium - Chambers April 2022
- Lower Magnesium, 6 percent more COVID - Feb 2022
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 etc. – June 2021
- Elderly nutrition and COVID-19 – systematic review July 2021
- Magnesium in Infectious Diseases in Older People - Jan 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- 6X less risk of COVID-19 ICU if Vitamin D and Vit B12 and Mg – Jan 2021
- Cytokine storms (COVID-19, etc.) eliminated by Vitamin D (Magnesium helps)
- Magnesium and Vitamin D deficiencies associated with worse COVID-19 – Jan, 2021
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- Magnesium (which increases vitamin D) may fight COVID-19 - Oct 2020
- COVID-19 1.8 X more likely if proton pump inhibitor (decreases Mg and Vitamin D) – Aug 2020
- COVID-19 might be treated with Mg IV and Potassium – July 2020
- COVID-19 prompts awareness of deficiencies of Vitamin D, C and Magnesium - April 6 2020
- Obesity pandemic since 1975 - is it due to Vitamin D, Magnesium, Iodine, adenovirus, or what
Optimal levels speculation
- <10% of the population have an optimal level of Vitamin D or Omega-3 or Magnesium
- < 2% of the population have optimal levels of all three
- It appears difficult to have an optimal level in one of the nutrients without having at least an OK level in the other two
Fun Fact - Olympics committee has declared that supplementing with Vitamin D and Omega-3 is useful and is not "doping"
 Download the PDF from VitaminDWiki
Arash Asher, Nathan L. Tintle2,3, Michael Myers4, Laura Lockshon1, Heribert Bacareza5, and William S. Harris,6 wsh at faresinst.com
1Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles, CA.
2Fatty Acid Research Institute, Sioux Falls, SD
3Department of Mathematics and Statistics, Dordt University, Sioux Center, IA
4Los Alamitos Medical Center, Los Alamitos, CA
5Department of Medical Affairs, Cedars-Sinai Medical Center, Los Angeles, CA
6Department of Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SDVery-long chain omega-3 fatty acids (EPA and DHA) have anti-inflammatory properties that may help reduce morbidity and mortality from COVID-19 infection. We conducted a pilot study in 100 patients to test the hypothesis that RBC EPA+DHA levels (the Omega-3 Index, O3I) would be inversely associated with risk for death by analyzing the O3I in banked blood samples drawn at hospital admission. To have adequate power (>80%) in this pilot study, we pre-specified a significance level of 0.10. Fourteen patients died, one of 25 in quartile 4 (Q4) (O3I >5.7%) and 13 of 75 in Q1-3. After adjusting for age and sex, the odds ratio for death in patients with an O3I in Q4 vs Q1-3 was 0.25, p=0.07. Thus, we have suggestive evidence that the risk for death from COVID-19 was lower in those with the highest O3I levels. These preliminary findings need to be confirmed in larger studies.
4X fewer COVID-19 deaths in those having high Omega-3 index – Jan 6, 20212678 visitors, last modified 13 Jan, 2021, This page is in the following categories (# of items in each category)