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Autism treated by an activator of the Vitamin D Receptor: supforaphane - March 2024


New Study Shows Promise for Natural Support of Autism Symptoms - March 2024

GreenMedInfo

  • "A new double-blind, placebo-controlled study published in Psychiatry and Clinical Neurosciences shows exciting potential for sulforaphane, a compound found in broccoli sprouts, to help ease symptoms of irritability and hyperactivity in children with autism spectrum disorder (ASD)."
    • "After 10 weeks, the sulforaphane group showed significantly greater improvements in irritability scores and hyperactivity/noncompliance scores compared to placebo. However, no differences were seen between groups in other symptom areas like lethargy, stereotypic behavior, or inappropriate speech."
  • " A study published in Psychiatry and Clinical Neurosciences found that when used as an adjunctive treatment alongside risperidone, sulforaphane significantly improved symptoms of irritability and hyperactivity in children with ASD compared to placebo."
  • "Early studies associate sulforaphane with reduced risks for cardiovascular disease, asthma, schizophrenia, Alzheimer's disease, and Parkinson's disease.8 It has been shown to support liver function, blood sugar balance, eye health, skin reactions, detoxification and even slowing the aging process itself. With over 250 recorded health benefits, sulforaphane's therapeutic potential appears tremendous.9"
  • Momtazmanesh, S., Amirimoghaddam-Yazdi, Z., Moghaddam, H.S., Mohammadi, M.R. and Akhondzadeh, S., 2020. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatry and Clinical Neurosciences, 74(7), pp.398-405.
  • Note: there appears to be no mention in the article that sulforaphane is a VDR activator
  • https://greenmedinfo.com/substance/sulforaphane has 624 abstracts as of April 2024

VitaminDWiki - Activators of the Vitamin D Receptor include sulforaphane and curcumin – June 2020


VitaminDWiki - 5 studies in both categories Autism and Vitamin D Receptor

This list is automatically updated


VitaminDWiki – Autism category contains:

Autism category has 155 items

 - see also Overview Autism and vitamin D,  Autoimmune ,   Cognitive,    ADHD
Interesting Autistic studies
Autism associated with low Vitamin D

Autism treated by Vitamin D

Autism reduced by vitamins before and during pregnancy

Autism and Vitamin D Receptor (not enough Vit D gets to the cells)
This list is automatically updated

Autism - other risk factors

Autism and Virus/Vaccines
This list is automatically updated

Dr. Cannell on Autism and Vitamin D in VitaminDWiki

Autism and Omega-3
This list is automatically updated


VitaminDWiki - The risk of 50+ diseases at least double with poor Vitamin D Receptor


VitaminDWiki - Vitamin D Receptor activation can be increased in many ways

Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin,   Berberine,  intense exercise, Butyrate   Sulforaphane   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 16 known VDR activators


VitaminDWiki – The Vitamin D Receptor is associated with many health problems

516 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

See also: 47 studies in the Resveratrol category

It appears that 30% of the population have a poor VDR (40% of the Obese )
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
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The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (19 studies), Breast Cancer (22 studies), Colon Cancer (13 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (24 studies), Hypertension (9 studies), Infant (22 studies), Lupus (6 studies), Metabolic Syndrome (4 studies), Mortality (4 studies), Multiple Sclerosis (12 studies), Obesity (17 studies), Pregnancy (24 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (36 studies),   Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation

55 health problems associated with poor VDR


A poor VDR is associated with the risk of 55 health problems  click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023  click here for details
Some health problem, such as Breast Cancer reduce the VDR

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR


How to increase VDR activation


Compensate for poor VDR by increasing one or more:

IncreasingIncreases
1) Vitamin D supplement  Sun
Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
etc
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D Receptor
13) Sulfroaphane and perhaps sulfurVitamin D Receptor
14) Butyrate especially gutVitamin D Receptor
15) BerberineVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR