Stroke or coronary heart disease deaths 30% less likely if had taken more than 440 IU of vitamin D (900,000 patient years) – Jan 2018

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease – The Japan Collaborative Cohort Study

Stroke. 2017; https://doi.org/10.1161/STROKEAHA.117.019417
Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano,, Hiroyasu Iso, Akiko Tamakoshi

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Stroke
Overview Stroke and vitamin D
Vitamin D associated with 50 percent less ischemic stroke – meta-analysis Aug 2012
Stroke mortality 3X worse among seniors with less than 26 ng of vitamin D – June 2014
Large vessel Ischemic Stroke 13 X more likely if low vitamin D – Nov 2017
Stroke 74% less likely if high vitamin D (7,295 women 20-50 years old) – July 2017
Stroke results in 8 years of cognitive decline (vitamin D not mentioned) May 2015
Cardiovascular
Overview Cardiovascular and vitamin D
Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
Cardiovascular Diseases and Vitamin D – Review Feb 2015
7X increased chance of death if coronary artery disease and low vitamin D – Oct 2013
Cardiovascular category starts with the following

507 items In Cardiovascular category

Cardiovascular category is associated with other categories: Diabetes 31, Omega-3 31 , Vitamin K 25 , Intervention 22 . Mortality 20 , Skin - Dark 18 , Magnesium 17 , Calcium 14 , Hypertension 14 , Trauma and surgery 13 , Stroke 13 , Kidney 12 , Metabolic Syndrome 11 , Seniors 10 , Pregnancy 8 as of Aug 2022


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Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.

Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals of mortality were calculated using categories of vitamin D intake.

Results—During 965 970 person-years of follow-up, 1514 stroke and 702 coronary heart disease deaths were documented. Vitamin D intake was inversely associated with risk of mortality from total stroke especially intraparenchymal hemorrhage but not from coronary heart disease; the multivariable hazard ratios (95% confidence intervals) for the highest (≥440 IU/d) versus lowest (<110 IU/D) categories of vitamin D intake were 0.70 (0.54–0.91; P for trend=0.04) for total stroke and 0.66 (0.46–0.96; P for trend=0.04) for intraparenchymal hemorrhage.

Conclusions—Dietary vitamin D intake seems to be inversely associated with mortality from stroke.

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