Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021

The coronavirus disease (COVID-19) – A supportive approach with selected micronutrients

Int. Journal for Vitamin and Nutrition Research. https://doi.org/10.1024/0300-9831/a000693
Uwe Gröber - Academy for Micronutrient medicine (AMM), Essen, Germany
Michael F. Holick - Boston University Medical Center, Massachusetts, USA

VitaminDWiki

Increase Vitamin D as soon as possible - to prevent infection or reduce symptom severity
If wait till hospital:
   Start with initial bolus dose of 50,000 - 200,000 IUs of vitamin D
   Followed by 50,000 - 60,000 weekly while in hospital

Note: >70% of the RCT using Vitamin D to fight COVID-19 are using
at least 100,000 IU during the first week

RCTs for COVID-19

COVID-19 treated by Vitamin D - studies, reports, videos

As of Jan 31, 2024, the VitaminDWiki COVID page had:  19+ trial results,   37+ meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   All 26 COVID risk factors are associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   166 COVID Clinical Trials using Vitamin D (Aug 2023)   Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries


Note: Zinc proven to treat colds when given every 2 hours. no knowlege of the dosing periods needed for COVID-19

Note: Two COVID-19 clinical trials are using a combination Vitamin D and Zinc

Virus and Zinc

 Download the PDF from VitaminDWiki

Zinc and COVID-19
Image

Worldwide the pandemic of COVID-19 spreads rapidly and has had an enormous public health impact with substantial morbidity and mortality especially in high-risk groups, such as older people and patients with comorbidities like diabetes, dementia or cancer. In the absence of a vaccine against COVID-19 there is an urgent need to find supportive therapies that can stabilize the immune system and can help to deal with the infection, especially for vulnerable groups such as the elderly. This is especially relevant for our geriatric institutions and nursing homes. A major potential contributing factor for elderly is due to their high incidence of malnutrition: up to 80% among the hospitalized elderly. Malnutrition results when adequate macronutrients and micronutrients are lacking in the diet. Often missing in public health discussions around preventing and treating COVID-19 patients are nutritional strategies to support optimal function of their immune system. This is surprising, given the importance that nutrients play a significant role for immune function.
Several micronutrients, such as

  • vitamin D,
  • retinol,
  • vitamin C,
  • selenium and
  • zinc

are of special importance supporting both the adaptive and innate immune systems. As suboptimal status or deficiencies in these immune-relevant micronutrients impair immune function and reduces the resistance to infections, micronutrient deficiencies should therefore be corrected as soon as possible, especially in the elderly and other vulnerable groups.
According to epidemiological, experimental and observational studies, some case reports and a few intervention studies the supplementation of vitamin D and/or zinc are promising. The multiple anti-inflammatory and immunomodulatory effects of Vitamin D could explain its protective role against immune hyper reaction and cytokine storm in patients with severe COVID-19. A randomized, placebo-controlled intervention study even shows that high dose vitamin D supplementation promotes viral clearance in asymptomatic and mildly symptomatic SARS-CoV-2 positive individuals. Besides, the data of a recent prospective study with COVID-19 patients reveal that a significant number of them were zinc deficient. The zinc deficient patients had more complications and the deficiency was associated with a prolonged hospital stay and increased mortality. Thus, immune-relevant micronutrients may help to increase the physiological resilience against COVID-19.
- - - - - -
Conclusion
The supplementation with micronutrients, including vitamin D and zinc is a safe, effective, and low-cost strategy to help support optimal immune function in times of respiratory tract infections with SARS-CoV-2. The application of immune-relevant micronutrients above the recommended
dietary allowance (RDA), but within recommended upper safety limits, for specific micronutrients such as vitamins D and zinc is urgently warranted, especially in vulnerable groups such as the elderly. Public health officials are encouraged to promote nutritional strategies in their recommendations to improve public health, especially in vulnerable groups such as the elderly

VitaminDWiki pages with HOLICK in title (47 as of April 2022)

This list is automatically updated

Items found: 52
Title Modified
Should You Take A Vitamin D Supplement - Dr Holick transcript Oct 2022 28 Nov, 2023
Vitamin D: 100 year anniversary of discovery – Holick Jan 2023 23 Jan, 2023
Vitamin D and neurocognitive function – Holick April 2014 21 Oct, 2022
Vitamin D and neurocognitive function – Holick Oct 2022 21 Oct, 2022
How Sensible Sun Exposure Benefits Your Health -Holick interview May 2022 30 May, 2022
UV, sunshine, and vitamin D (87 charts) - Holick March 2013 11 Jan, 2022
Vitamin D and COVID-19: a narrative review - Holick - Jan 4, 2022 10 Jan, 2022
Low Vitamin D in infants - video interview of Dr. Holick - May 2017 11 Dec, 2021
Hospital has banned Dr. Holick due to testifying in cases of infants with broken bones- August, 2021 03 Aug, 2021
Vitamin D Is Not as Toxic as Was Once Thought – Holick May 2015 20 Mar, 2021
Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021 28 Jan, 2021
A call to action: Vitamin D for hip fracture (50,000 weekly for 8 weeks, then bi-weekly – Holick July 2020 11 Dec, 2020
Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020 17 Sep, 2020
Immunologic Effects of Vitamin D on Human Health and Disease - Holick July 2020 15 Jul, 2020
The vitamin D deficiency pandemic – Holick May 2017 21 Jan, 2020
Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019 25 Jun, 2019
Diagnosis and treatment of osteopenia – Holick 2010 10 Dec, 2018
Photobiology of Vitamin D – free chapter in book – Holick 2010 17 Nov, 2018
Kaiser Health News wrote a damning article about Dr. Holick and Vitamin D, NYT published it – Aug 2018 20 Aug, 2018
Vitamin D - at least 4,000 IU to achieve 40-60 ng and reduce risk of early death – Holick June 2018 04 Jun, 2018
Role of Vitamin D in the Pathogenesis of Diabetes – Holick July 2017 16 Jul, 2017
The risks and benefits of sun exposure – Holick Oct 2016 05 Jan, 2017
Vitamin D presentation by Dr. Holick Spring 2012 08 Mar, 2016
Holick interview by Mercola on Vitamin D – Dec 2015 17 Jan, 2016
Major review of Vitamin D – Holick Feb 2013 27 Dec, 2015
Vitamin D Global Perspective - Holick June 2013 27 Dec, 2015
Dr. Holick video on vitamin D - March 2013 27 Dec, 2015
Vitamin D from 1940 and into the future – Holick video Nov 2013 28 Nov, 2015
Vitamin D review – Holick Jan 2013 24 Sep, 2015
Go ahead, soak up some sun (but don’t burn) – Holick July 2015 01 Aug, 2015
Chicago Sun Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010 15 Jul, 2015
Chicago Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010 15 Jul, 2015
Live Longer with Vitamin D - Holick March 2015 17 May, 2015
Sunlight and Your Health: An EnLIGHTening Perspective - Holick Video Dec 2014 14 Mar, 2015
Less sun means more disease -Grant, Holick, Cannell, et al Feb 2015 05 Mar, 2015
Cancer, Sunlight, and Vitamin D - Holick Oct 2014 06 Oct, 2014
Environmental factors that influence the cutaneous production of vitamin D – Holick 1995 06 Jan, 2014
If You're Low in This Nutrient, It Doubles Your Odds of Many Cancers– Interview Dr. Holick Oct 2013 23 Dec, 2013
Patent application for a skin cream which enhances production of vitamin D – Holick July 2013 24 Nov, 2013
Vitamin D update – Holick Sept 2013 11 Nov, 2013
Vitamin D, Sunlight and Cancer Connection – Holick Jan 2013 11 Aug, 2013
Vitamin D encyc. - 2nd edition, Holick - April 2013 02 Mar, 2013
Major review of Vitamin D – Holick 2013 part II 08 Feb, 2013
Vitamin D: A D-Lightful Vitamin for Health – Holick Dec 2012 07 Jan, 2013
Evidence for vitamin D – Holick June 2012 23 Nov, 2012
VITAMIN D: A D-LIGHTFUL SOLUTION FOR GOOD HEALTH – Holick 2012 30 Oct, 2012
Michael Holick – reduce health care costs 25 percent – interview Sept 2010 07 Oct, 2012
High Prevalence of Vitamin D Inadequacy - Holick Mayo Clinic 2006 14 May, 2012
Professional book on Vitamin D - Editor Holick 2010 27 Aug, 2011
Vitamin D Holick – Jan 2011 29 Mar, 2011
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