Cancer risk among patients with type 2 diabetes: A real‐world study in Shanghai, China
Journal of Diabetes 08 May 2019 https://doi.org/10.1111/1753-0407.12926
Jiying Qi Ping He Huayi Yao Ruogang Song Chenglong Ma Min Cao Bin Cui Guang Ning
- Pancreatic cancer 80 percent more likely if person had diabetes for 2-8 years – Jan 2013
- ALL of the top 10 health problems of women are associated with low vitamin D
- Mortality increased: 4X Cancer, 5X Diabetes if eat a lot of meat protein – March 2014
- Perhaps the connection is MEAT protein
Diseases that may be related via low vitamin D has the following
- Depression <==> Diabetes
- Diabetes ==> Cognitive impairment
- Diabetes ==> Vertebral fracture in men only
- Diabetes ==> Rheumatoid Arthritis
- Diabetes ==> PCOS women
- PCOS ==> Diabetes
- Periodontitis + Low Vit D ==>Diabetes 2.8X
- Diabetes ==> Pancreatic Cancer
- Diabetes ==> Cancers
- Diabetes ==> Alzheimer's
- Diabetes (T1) ==> Multiple Sclerosis
- Diabetes ==> Parkinson's
Cancer category starts with the following
- Cancer
292 items Overview Cancer and vitamin D - Cancer and Vitamin D - many studies
- After Cancer Diagnosis
113 items - Bladder Cancer
28 items - Breast Cancer
256 items Overview Breast Cancer and Vitamin D - Colon Cancer
144 items Overview Cancer-Colon and vitamin D - Leukemia
19 items - Liver Cancer
17 items - Lung Cancer
55 items Overview Lung cancer and vitamin D - Lymphoma Cancer
26 items - Other Cancer
66 items - Ovarian Cancer
26 items - Pancreatic Cancer
57 items - Prostate Cancer
103 items Overview Prostate Cancer and Vitamin D - Skin Cancer
121 items Overview Suntan, melanoma and vitamin D - Childhood Cancers - Vitamin D can help - many studies
- Easiest way to treat cancer – take Vitamin D – Nov 2022
- 13 Cancers are helped by Vitamin D – Biobank July 2023
- 2X increase of 14 cancers in non-seniors in 20 years (low vitamin D) – Sept 2022
- Vitamin D prevents and treats cancer in many ways – May 2021
- Those with recent cancer diagnosis had 7X increased risk of COVID-19 (more if A-A )- Dec 2020
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Cancer incidence and mortality is decreased if 40-60 ng of Vitamin D – April 2019
- 8 ways that Cancer might be prevented by Vitamin D - June 2019
- Cancer stem cells and Vitamin D - many studies
- Vitamin D Reduces Cancer Risk - Why Scientists Accept It but Physicians Do Not - Feb 2019
- Overview of Vitamin D Actions in Cancer – 31 page chapter in a book – 2018
- Vitamin D prevents breast cancer, reduces BC mortality, and reduces BC chemotherapy problems – Sept 2018
- Diagnosed with breast cancer – take vitamin D to cut chance of death by half – July 2018
- Melanoma 25 X more likely if low vitamin D – Feb 2018
- Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)– Aug 2018
Cancers get less Vitamin D when there is a poor Vitamin D Receptor- Vitamin D Receptor pages in VitaminDWiki with CANCER in title 86 as of July 2023
- Cancer and the Vitamin D Receptor, a primer – Sept 2017
- Vitamin D Receptor (Cancers OR Viruses) - many studies
- Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016
- Cancer (general) and VDR
23 articles - Breast Cancer and VDR
23 articles - Colon Cancer and VDR
13 articles - Prostate Cancer and VDR
7 articles - Skin Cancer and VDR
10 articles - Note some Health problems, such as some Cancers, protect themselves
by actively reducing Receptor activation
From the web
- Diabetes ==> Cancer Hypothesis, Nov 2012; Boucher BJ and others
Background
The aim of this study was to investigate the risk of 23 common types of cancer among patients with type 2 diabetes (T2D) compared with the general Chinese population.Methods
Based on the Shanghai Hospital Link database, 410 191 patients with T2D (age 20‐99 years) were identified from July 2013 to December 2016, and were followed‐up for cancer incidence until December 2017.Results
In all, 8485 cases of newly diagnosed cancer were identified. The standardized incidence ratios (SIRs) of total cancer were 1.34 and 1.62 among males and females, respectively. Among males with T2D, the risk of cancer of the prostate (highest SIR of 1.86), blood (leukemia, lymphoma), skin, thyroid, kidney, liver, pancreas, lung, colorectum, and stomach was increased significantly. There was a significant decrease in the risk of esophageal cancer.
In females with T2D, there were significantly greater risks of cancer of the- nasopharynx (highest SIR of 2.33),
- liver,
- esophagus,
- thyroid,
- lung,
- pancreas,
- blood (lymphoma, leukemia),
- uterus, colorectum,
- breast,
- cervix, and
- stomach.
In contrast, there was significantly decrease risk of gallbladder cancer in females with T2D.
Conclusions
This study shows significantly increased risks of overall and some site‐specific cancers among patients with T2D. We suggest that establishing strategies for regular cancer‐specific screening and prevention care among patients with T2D are necessary.Funding information: National Key R&D Program of China, Grant/Award Number: 2016YFC1305500; National Natural Science Foundation of China, Grant/Award Numbers: 81670799, 81570707, 81702642; Shanghai Municipal Education Commission‐Gaofeng Clinical Medicine Grant, Grant/Award Number: 20152502; Shanghai Sailing Program, Grant/Award Number: 16YF1409800
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