Vitamin D benefits Matrix - Examine May 2013

The risk of falls in the elderly (and subsequently, rate of bone fractures) appears to be significantly reduced with Vitamin D supplementation at 700 IU or greater, with... show

There appears to be less risk of cardiovascular disease and related cardiovascular complications with supplementation of 1,000 IU of Vitamin D or higher serum levels of... show

The association between serum Vitamin D at 37ng/mL and colorectal cancer is is approximately a halving of risk according to one meta-analysis, which is a notable risk reduction

A decrease in bone fracture risk (nonvetebral and hip) appears to exist when supplemental doses of Vitamin D3 are taken above 800 IU, with this protective effect being... show

Both correlational and intervention studies note that higher cohorts of serum Vitamin D have less blood pressure than lower cohorts, establishing a role for Vitamin D in... show

Vitamin D supplementation is the reference drug for reductions in parathyroid hormone due to directly negatively regulating its secretion

Mixed effects on overweight/obese persons, but it appears that normalizing a deficiency may aid fat loss in persons of higher body weight. Insufficient evidence to suggest... show

Cohorts of people with higher serum Vitamin D appear to die less frequently than cohorts with less serum Vitamin D; this may be heavily influenced by reducing falls in... show

An improvement in insulin secretion is noted in diabetics (type II mostly) and in persons at risk for diabetes, which is thought to be secondary to protective effects at... show

Improvements in insulin sensitivity can occur secondary to increasing pancreatic insulin secretion

No significant alterations noted in weight, even when fat mass is lost, in obese persons

The decrease in triglycerides is present after long term ingestion of Vitamin D, although it isn't to a highly significant degree

A decrease has been noted over time relative to placebo, of relatively minor magnitude

Either no significant influence on LDL cholesterol or a slight increase (around 5%) has been noted; practical significance of this information unknown

No detectable influence on metabolic rate over time

May reduce the risk of catching the flu

Persons with higher serum vitamin D appear to have less frequency asthmatic attacks relative to persons with lower Vitamin D levels

An increase in testosterone has been noted in men with 3,332 IU of Vitamin D over the course of a year

An improvement in muscular and neural functionality in the elderly is thought to underlie the reductions of fall risk and reduced bone fracture rate seen in elderly cohorts

The decrease in HbA1c is statistically insignificant and very small in magnitude, likely not a concern.

An increase in IL-5 has been noted with Vitamin D supplementation

An increase in lean mass has been noted in dieting obese women relative to control (2,000IU) and a trend to reduce lean mass relative to control has been noted in exercising... show

No significant alterations in food intake noted with Vitamin D supplementation

No significant influence on endothelial function

No significant influence on select inflammatory cytokines

Superloading Vitamin D (rather than staying sufficient) does not appear to further increase absorption rates of calcium, although normalizing a deficiency can aid in absorption... show

Inflammatory symptoms associated with Lupus appear to be reduced with Vitamin D ingestion

Lack of efficacy in reducing rate of sickness

A higher vitamin D level in serum during growth spurts in children is associated with greater heights during adulthood; currently no evidence to support the role of Vitamin... show

A decrease in symptoms associated with tuberculosis are noted with Vitamin D

No significant influence on fasting insulin levels

No significant influence on fasting blood glucose levels

Although a trend to increase power output has been noted, most research suggest no such benefit

The risk of developing MS is significantly reduced by both sunlight, latitude, and supplemental Vitamin D

There is less risk of breast cancer associated with Vitamin D supplementation

Appears to be associated with less risk of pancreatic cancer

May reduce symptoms of athralgia

May reduce the incidence of type 1 diabetes in offspring and adults when supplemented (for the former, but the mothers)

There appears to be a lower relapse rate in multiple sclerosis patients when Vitamin D is present at higher concentrations