Vitamin D supplementation is associated with slower epigenetic aging - May 2022


Vitamin D supplementation is associated with slower epigenetic aging

GeroScience https://doi.org/10.1007/s11357-022-00581-9
Valentin Max Vetter • Yasmine Sommerer, Christian Humberto Kalies • Dominik Spira •, Lars Bertram • Ilja Demuth

Study summary by vitaminDWiki

1,000 seniors living in Berlin

  • Took 5 gene aging tests and a Vitamin D test
  • 7 years passed
  • Again took the same 5 gene aging tests and a Vitamin D test

Some of the Germans who had been deficient (<20 ng) supplemented got to >30 ng
The ("treated") aged more slowly (a negative score) than those who did not supplement
For most of the tests, they aged even less than those who had been > 30 ng
For all of the tests, they aged less (more negative scores) than those who remained deficient

Image
Adverse effects of low vitamin D level on mortality and morbidity are controversially discussed. Especially older people are at risk for vitamin D deficiency and therefore exposed to its potentially harmful consequences. A way of measuring differences in the biological age is through DNA methylation age (DNAm age) and its deviation from chronological age, DNAm age acceleration (DNAmAA). We previously reported on an association between vitamin D deficiency and higher 7-CpG DNAmAA in participants of the Berlin Aging Study II (BASE-II). In this study, we employ a quasi-interventional study design to assess the relationship between DNAmAA of five epigenetic clocks and vitamin

 Download the PDF from VitaminDWiki


VitaminDWiki pages with EPIGENETIC in title (16 as of June 2022)

This list is automatically updated

Items found: 19
Title Modified
Vitamins etc, appear to slow down epigenetic aging and reduce inflammation – March 2024 26 Mar, 2024
Epigenetics and Vitamin D – many studies 23 Oct, 2023
Vitamin D Health problems can run in families (epigenetics, they miss other reasons) – June 2023) 16 Jun, 2023
Vitamin D supplementation is associated with slower epigenetic aging - May 2022 21 Jun, 2022
Epigenetics, vitamin D, and Multiple Sclerosis 15 Jun, 2022
Epigenetics - PDFs and links, with and without Vitamin D 25 Feb, 2021
Epigenetics identified Cervical Cancer 100 percent of time – 2019 23 Dec, 2019
Stressors as a fetus or child can cause health problems in adult (perhaps via epigenetics) – Dec 2017 14 Oct, 2018
Health problems can persist through many generations – Epigenetics and Vitamin D 13 Oct, 2018
Epigenetics meets endocrinology – 2011 13 Oct, 2018
Vitamin D Receptor – environment, genetics and epigenetics – May 2015 13 Oct, 2018
Low vitamin D in pregnancy – epigenetic pancreas problems in offspring (mice) – May 2016 05 May, 2016
Epigenetics of Multiple Sclerosis – March 2014 06 Sep, 2015
Micronutrients, methylation, epigenetics, longevity podcast by Rhonda Patrick and Tim Ferriss - June 2015 22 Jun, 2015
Epigenetics meets endocrinology - 2011 21 Jan, 2015
Hypothesis: Epigenetics, vitamin D, and Multiple Sclerosis – Nov 2012 29 Aug, 2014
Epigenetics of prostate cancer and vitamin D – June 2010 09 Jul, 2013
Lung disease, vitamin D, and epigenetics – Aug 2011 13 Feb, 2012
Epigenetics and vitamin D – June 2010 clips from the web 05 Jun, 2010

Epigenetic Role of Vitamin D: 56 minute video - May 2022

Dr. Eduardo Beltran
An Epigenetic Approach for Treating Autoimmune Diseases. HDVD Therapy + Anti-inflammatory Diet! In this presentation we will talk about:
1.) Dysbiosis
2.) Leaky Gut Syndrome Pathogenesis
3.) Relationship between Fiber-Mucin-Tight Junctions & Vitamin D3
4.) Leaky Brain Syndrome
5.) Fetal Susceptibility Hypothesis
6.) Nutrigenomics and SNPs
7.) Vitamin D Genes and SNPs
8.)VDR Cleansing Through Diet Modification (Anti-inflammatory Diet)


Vitamin D and Omega-3 may reverse epigenetic aging - Drs. Patrick and Horvath video May 2022

video
Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
Note: Horvath is the name of one of the aging clocks in the German study


Epigenetics & "vitamin d" in Google Scholar: includes 6 studies with PDFs

30,000 Items as of June 2022

  • Vitamin D supplementation is associated with slower epigenetic aging = May 2022 PDF
  • Epigenetic Clock: A Novel Tool for Nutrition Studies of Healthy Ageing - April 2022 PDF
  • Epigenetic Aging in Early Life: Role of Maternal and Early Childhood Nutrition - Feb 2022 PDF
  • Epigenetics in Food Allergy and Immunomodulation - Dec 2021 PDF
  • Analysis of epigenetic changes in vitamin D pathway genes in rheumatoid arthritis patients - 2021 PDF
  • Vitamin D: a Review of its Effects on Epigenetics and Gene Regulation - Dec 2020 PDF
  • Epigenetics Predicts Serum 25-Hydroxyvitamin D Response to Vitamin D 3 Supplementation in African Americans - Jan 2020 https://doi.org/10.1002/mnfr.201900738
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