Reduce 4 health problems by a quarter if increase Vitamin D to 30 ng – Saudi Arabia, Grant March 2023


Evidence That Increasing Serum 25(OH)D Concentrations to 30 ng/mL in the Kingdom of Saudi Arabia and the United Arab Emirates Could Greatly Improve Health Outcomes

Biomedicines 2023, 11(4), 994; https://doi.org/10.3390/biomedicines11040994
by William B. Grant 1ORCID,Fatme Al Anouti 2,*ORCID,Barbara J. Boucher 3ORCID,Hana M. A. Fakhoury 4ORCID,Meis Moukayed 5ORCID,Stefan Pilz 6 and Nasser M. Al-Daghri 7,*ORCID

  • 1 Sunlight, Nutrition, and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603, USA
  • 2 Department of Health Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi P.O. Box 144534, United Arab Emirates
  • 3 The Blizard Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London E12AT, UK
  • 4 Department of Biochemistry and Molecular Medicine, College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia
  • 5 School of Arts and Sciences, American University in Dubai, Dubai P.O. Box 28282, United Arab Emirates
  • 6 Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria
  • 7 Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia

*Authors to whom correspondence should be addressed

PDF Table of Contents
Image

Accumulating evidence supports the potential protective effects of vitamin D against chronic diseases such as

  • Alzheimer’s disease,
  • autoimmune diseases,
  • cancers,
  • cardiovascular disease (ischaemic heart disease and stroke),
  • type 2 diabetes,
  • hypertension,
  • chronic kidney disease,
  • stroke, and infectious diseases such as acute respiratory tract diseases,
  • COVID-19,
  • influenza, and pneumonia, as well as
  • adverse pregnancy outcomes.

The respective evidence is based on ecological and observational studies, randomized controlled trials, mechanistic studies, and Mendelian randomization studies. However, randomized controlled trials on vitamin D supplementation have largely failed to show benefits, probably due to poor design and analysis. In this work, we aim to use the best available evidence on the potential beneficial effects of vitamin D to estimate the expected reduction in incidence and mortality rates of vitamin D-related diseases in the Kingdom of Saudi Arabia and the United Arab Emirates if minimum serum 25(OH)D concentrations were to be raised to 30 ng/mL.
Estimated reductions by

  • 25% for myocardial infarction incidence,
  • 35% for stroke incidence,
  • 20 to 35% for cardiovascular disease mortality, and
  • 35% for cancer mortality rates

depicted a promising potential for raising serum 25(OH)D.
Methods to increase serum 25(OH)D concentrations at the population level could include

  • food fortification with vitamin D3,
  • vitamin D supplementation,
  • improved dietary vitamin D intake, and
  • sensible sun exposure.

 Download the PDF from VitaminDWiki


49+ VitaminDWiki pages have GRANT in their title

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Items found: 52
Title Modified
Increasing the vitamin D level of all Canadians to 40 ng would save 6 to 18 billion dollars a year – Grant Nov 2016 23 Aug, 2023
Periodontal Disease and Vitamin D - interview and transcript - GRH, Grant July 2023 02 Aug, 2023
Dental problems if low Vitamin D (Hill's, Global Rec.) - Grant June 2023 02 Aug, 2023
Yes, Vitamin D can be a magic bullet - Grant March 2020 01 Aug, 2023
Reduce 4 health problems by a quarter if increase Vitamin D to 30 ng – Saudi Arabia, Grant March 2023 17 May, 2023
The Role of Vitamin D in Reducing Risk of Alzheimer’s and Dementia - transcript Dr. Grant March 2023 12 Mar, 2023
My Life as a Vitamin D Researcher – Dr. Grant Feb 2023 19 Feb, 2023
The Real Story on Vitamin D: interview and transcript – Grant Dec 2022 10 Dec, 2022
African American Health Disparities are associated with low Vitamin D - Grant Feb 2021 10 Dec, 2022
Vitamin D should reduce hospital-acquired infections – Grant Dec 2012 10 Dec, 2022
Increase life expectancy by 2 years if double vitamin D levels – Grant July 2011 09 Dec, 2022
Mortality reduced by 35 percent if everyone had 50 ng of vitamin D - Grant Oct 2021 09 Dec, 2022
Interview with transcript concerning UVA, UVB, and health – Grant Dec 2012 09 Dec, 2022
Dr. Grant on vitamin D and mortality in VitaminDWiki 09 Oct, 2022
Mortality reduced if Vitamin D levels raised to 30 ng ( Middle East this time) - Grant Oct 2022 09 Oct, 2022
Debunking Misinformation About Vitamin D - Grant podcast and transcript - Sept 2022 21 Sep, 2022
The problems with healthcare in the U.S., following the disinformation playbook – Grant Dec 2017 23 Jun, 2022
Interview with transcript of Dr. Grant on Vitamin D and Cancer by Dr. Moss - June 2022 23 Jun, 2022
By Dr. Grant in VitaminDWiki 01 Mar, 2022
Vitamin D benefits ignored at a time they are most needed - Grant Jan 9, 2022 10 Jan, 2022
Top Vitamin D Papers - Grant 2017 09 Jan, 2022
Top 25 Vitamin D Publications in 2020 - Grant 09 Jan, 2022
Cancer incidence and death reduced by both Vitamin D and UVB – Grant Oct 2021 15 Oct, 2021
Vitamin D and Health video with transcript - Dr. Grant Sept 2021 11 Sep, 2021
Vitamin D and COVID-19: Video and PDF by Dr. Grant (includes recommendations)- Nov 25, 2020 26 Nov, 2020
Preventing a COVID-19 pandemic with Vitamin D – Grant April 2020 02 Apr, 2020
Top Advances in the Understanding of Vitamin D on Human Health - Grant Jan 2019 19 Jan, 2020
Breast, Prostate and Colon Cancers are still strongly associated with low Vitamin D – Grant Jan 2020 01 Jan, 2020
Evidence that Vitamin D prevents Cancer – Grant Feb 2018 29 Jan, 2018
Vitamin D Video 53 minutes with text and PDFs – Grant Oct 2017 28 Nov, 2017
Canadian grant funding lost for prescribing 50,000 IU of vitamin D – July 2017 23 Jul, 2017
Pregnancy and Vitamin D bibliography - Dr. Grant - March 2017 20 Mar, 2017
Bibliography of Black-White health disparities linked to vitamin D - Dr. Grant March 2017 20 Mar, 2017
Prenancy and Vitamin D biliogrraphy - Dr. Grant - March 2017 20 Mar, 2017
Patent granted for adding vitamin D to sunblock and skin cream - Feb 2011 05 Jan, 2017
Optimum Vitamin D level: Evidence for 30 and 40 ng – Grant Aug 2013 28 Feb, 2016
Low UVB (thus low Vitamin D) is linked to many diseases – Grant Jan 2016 10 Jan, 2016
Time-release form of active vitamin D granted a patent for chronic kidney disease – July 2014 26 Jul, 2015
Vitamin D2 patent granted to prevent hair loss during chemotherapy – 2002 11 May, 2015
Less sun means more disease -Grant, Holick, Cannell, et al Feb 2015 05 Mar, 2015
Autism and vitamin D: Cannell, Grant – March 2013 05 Jan, 2015
Evidence that the minimum vitamin D blood level is 30 ng – Grant Nov 2012 21 Jan, 2014
Summary of Vitamin D trials - Grant Nov 2012 18 Jan, 2014
Solar UVB reduces Cancer Risk – Grant, Jan 2013 02 Oct, 2013
UK Day-Cares being offered grants to develop vitamin D methods – July 2012 27 Dec, 2012
Getting sunshine improves your health provided you do not sunburn - Grant Dec 2012 11 Dec, 2012
Review of Vitamin D trials - Grant Jan 2012 25 Nov, 2012
Abu Dhabi 2012 - Grant 11 Apr, 2012
Evidence for Vitamin D - Grant Aug 2011 09 Nov, 2011
Some cancer due to low UV – Grant – April 2010 13 Oct, 2011
Recommend 2500-4000 IU per day to reduce all-cause mortality by 18%– Grant Netherlands April 2010 13 Jul, 2011
Vitamin D overview by Grant - Jan 2011 13 Jul, 2011

21+ VitaminDWiki pages have SAUDI in their title

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Items found: 22
Title Modified
Low Vitamin D is associated with risk of Depression 5X, Stress 4.8 X, and Anxiety 3.9 X (Saudi Arabia college students) – July 2023 29 Jul, 2023
Reduce 4 health problems by a quarter if increase Vitamin D to 30 ng – Saudi Arabia, Grant March 2023 17 May, 2023
Possible large Vitamin D intervention trial: Iceland, Saudi Arabia etc. 03 Nov, 2022
Inflammatory markers reduced by single 80,000 IU of vitamin D (Saudi) – Sept 2022 24 Sep, 2022
Low vitamin D is big problem during pregnancies (Saudi Arabia in this case) – Aug 2022 25 Jul, 2022
Poor sleep associated with low Vitamin D (pregnant Saudis in the case) – Jun 2022 09 Jul, 2022
Saudi females twice as likely to be vitamin D deficient as males (cloth) – July 2015 27 Dec, 2021
Vitamin D levels increased in Saudi Arabia over a decade (more sun or supplements) – Sept 2021 07 Jun, 2021
Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020 12 Dec, 2020
2,000 IU vitamin D is the smallest dose in Saudi Arabia (GCC statement) – March 2020 04 Mar, 2020
Many fertilization and pregnancy problems associated with low vitamin D in Saudi Arabia – April 2018 21 Apr, 2018
Saudi infants – 4 in 10 have low Vitamin D, 8 in 10 have low Calcium (hypocalcemia) – March 2018 18 Mar, 2018
Saudi pregnancies – only 1 in 16 had even 20 nanograms of vitamin D – Nov 2015 28 Nov, 2015
70 pcnt of Saudi women were extremely vitamin D deficient, but only 40 pcnt of men – March 2012 18 Jul, 2015
Undetected Celiac Disease found in 2 percent at Saudi medical college – May 2015 01 May, 2015
Painful to be a female Saudi teacher (very low vitamin D) – Nov 2014 24 Mar, 2015
Diabetes in Saudi women improved with just 2,000 IU of vitamin D – July 2012 16 Mar, 2015
84 percent had less than 30 ng of vitamin D (10,000 patients in Saudi Arabia) Sept 2014 26 Sep, 2014
Saudi have very little vitamin D fortification of food - April 2013 02 Jul, 2013
Why do Saudi postmenopausal women have higher level of vitamin D – Mar 2011 03 Nov, 2012
Less than 20 ng of vitamin D associated with lumbar spine density in Saudi men – April 2011 01 Jun, 2011
Less than 4 ng is more common in Saudis than diabetic Saudis – July 2010 18 Jul, 2010

Getting most of the population >50 ng would provide far more benefits

Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and transcript - March 2023


Saudi Arabia needs Magnesium (most of their water has been desalinated)


Can get more Vitamin D from the sun without the heat (silver-coated plexiglass)


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