Olmesartan (blood pressure drug Benecar) improves Vitamin D Receptor by an unknown amount

  • When Olmesartan is taken at higher than normal dosing it apparently improved the Vitamin D Receptor
  • Unable to quickly find how much increase in VDR it actually provides
  • Benicar® Restores Vitamin D Receptor Competence June 2014
    Nice description with 20 references
  • Science behind olmesartan (Benicar) Marshal Protocol
    Safety of olmesartan
    Potent anti-inflammatory
    Vitamin D Receptor agonist
    Pharmacodynamics
    The unbound Vitamin D Receptor degrades quickly
    Infected cells have VDRs with a shorter life span
    Bacterial products down-regulate the expression of the VDR
    Pregnane X Receptor (PXR) agonist
    Other beneficial effects
    Cardiovascular disease
    Kidney disease
    Historical note: early insights into the necessity of frequent ARB dosing
    Other benefits of Olmesartan in patients - recent studies
    Related publications and presentations
    References
  • Ordering Olmesartan approx $1 per pill
  • Dosing: 1 pill every 4 hours thus the cost is ~$6/day
  • Bacterial Etiology of Chronic Illness Feb 2014
    Describes use of olmesartan to improve VDR

See also VitaminDWiki

Vitamin D Receptor category has the following

510 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

See also: 47 studies in the Resveratrol category

It appears that 30% of the population have a poor VDR (40% of the Obese )
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
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The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (19 studies), Breast Cancer (22 studies), Colon Cancer (13 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (24 studies), Hypertension (9 studies), Infant (21 studies), Lupus (6 studies), Metabolic Syndrome (4 studies), Mortality (4 studies), Multiple Sclerosis (12 studies), Obesity (16 studies), Pregnancy (24 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (36 studies),   Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation

55 health problems associated with poor VDR


A poor VDR is associated with the risk of 55 health problems  click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023  click here for details
Some health problem, such as Breast Cancer reduce the VDR

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR


How to increase VDR activation


Compensate for poor VDR by increasing one or more:

IncreasingIncreases
1) Vitamin D supplement  Sun
Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
etc
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D Receptor
13) Sulfroaphane and perhaps sulfurVitamin D Receptor
14)Butyrate especially gutVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR

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