Antenatal exposure to solar radiation and learning disabilities: Population cohort study of 422,512 children
Scientific Reports volume 9, Article number: 9356 (2019)
Claire E. Hastie, Daniel F. Mackay, Tom L. Clemens, Mark P. C. Cherrie, Albert King, Chris Dibben & Jill P. Pell
It is extremely important to get Sun, UVB, or at least Vitamin D before and during pregnancies
Note: This study is based on maxium possible ambient UVB during pregnancies and NOT
1) How much UVB was stopped by air pollution
2) How much UVB was stopped by clouds
3) How much UVB was stopped by clothes
4) How much much UVB was stopped by dark skin color
5) How much Vitamin D was lost due to obesity
- Low Vitamin D if low UV (Pregnant Japanese, 2012) – March 2019
- Conception in winter increases rate of Autism, learning disabilities, dyslexia – Oct 2016
- Poor cognition 26 percent more likely if low Vitamin D (29 studies) – meta-analysis July 2017
ADHD
- ADHD, Autism, Early Psychosis and Omega-3 – review Dec 2017
- ADHD 2 times more likely if poor Omega-6 to Omega-3 ratio – meta-analysis May 2016
- ADHD decreased by 11% for each 10 ng increase in vitamin D in early pregnancy – April 2015
- Increased risk of ADHD (28 pct.) and Autism (58 pct.) if low vitamin D during pregnancy – meta-analysis Jan 2019
Autism
- Autism risk reduced 2X by prenatal vitamins (Vitamin D or Folic) – Feb 2019
- Autism is the least in regions having the most sunshine (and vitamin D) – Nov 2017
- Health problems are related to birth month - June 2015
- Vitamin D and autism - treat: 300 IU per kg per day, prevent: during pregnancy 5,000 IU – Feb 2017
VitaminDWiki – Season of Birth category contains:
Season of birth is a good proxy for Vitamin D (for people far from the Equator)
Statistisically significant, but rarely greater than 20% change
Some health problems need Vitamin D in 2 or 3 trimesters, so are not associated with season
Perhaps some people in born in poor season will need more vitamin D all of their lives
Some Season of Birth studies
- Season of birth associated with many health problem (UK Biobank) – Nov 2020
- Preterm birth varies with season: 25 percent more likely if conception in autumn – Feb 2022
- Little sun in first trimester, 2.9 X more likely to have learning disabilities – June 2019
- UV at time of conception associated with Vitamin D Receptor activation 65 years later – Sept 2017
- Autoimmune Addison's Disease – increased risk if born in Dec or Jan – Nov 2016
- Schizophrenia increased 40 percent for Spring births after Danes stopped vitamin D fortification – April 2014
- Season of birth associated with Pneumonia (10 %) and Multiple Sclerosis (30 %) – May 2013
- Majority of Season of Birth health problems should vanish if take Vitamin D
100K monthly, or 50K bi-weekly, or 4K daily
- Diseases correlated to month of birth – 2008 has the following chart
Brain Development starts in first trimester
Ensure a healthy pregnancy and baby - take Vitamin D before conception has the following
Download the PDF from VitaminDWiki
Raw Data
First Timester portion of UVB table with annotations
Entire UVB Chart
Learning disability varies by month of conception. The underlying mechanism is unknown but vitamin D, necessary for normal brain development, is commonly deficient over winter in high latitude countries due to insufficient ultraviolet radiation. We linked the 2007–2016 Scottish School Pupil Censuses to Scottish maternity records and to sunshine hours and antenatal ultraviolet A/B radiation exposure derived from weather stations and satellites respectively. Logistic regression analyses were used to explore the associations between solar radiation, then ultraviolet B, and learning disabilities, adjusting for the potential confounding effects of month of conception and sex. Of the 422,512 eligible, singleton schoolchildren born at term in Scotland, 79,616 (18.8%) had a learning disability. Total antenatal sunshine hours (highest quintile; adjusted OR 0.89; 95% CI: 0.86, 0.93; p < 0.001) and ultraviolet B exposure (highest quintile; adjusted OR 0.55; 95% CI: 0.51, 0.60; p < 0.001) were inversely associated with learning disabilities with evidence of a dose-relationship. The latter association was independent of ultraviolet A exposure. Significant associations were demonstrated for exposure in all three trimesters. Low maternal exposure to ultraviolet B radiation may play a role in the seasonal patterning of learning disabilities. Further studies are required to corroborate findings and determine the effectiveness of supplements.
No statisitically significant relationship between low 1st trimester D levels and Leaning disorders - Sept 2021
Prenatal Vitamin D Levels in Maternal Sera and Offspring Specific Learning Disorders
Download the PDF from VitaminDWiki
1996, only about 10% had > 30 ng