Increased calcium intake is associated lower serum 25-hydroxyvitamin D levels in subjects with adequate vitamin D intake: a population-based observational study
BMC Nutrition v 6, # 49 (2020) Nov 2, DOI https://doi.org/10.1186/s40795-020-00381-4
Rolf Jorde & Guri Grimnes
Males red arrow is > 840 IU of vitamin D
Possible reason: high Calcium levels ==> Inflammation ==> Vitamin D used up
Some of the problems of excess Calcium (which causes inflammation) may be decreased by
- Magnesium
- Vitamin K
- Water
- Consuming Calcium from plants not rocks
Calcium hazards and bioavailability has the following
- All items with Calcium in VitaminDWiki
220 items - Calcium from food or supplements associated with more deaths (US Cohort of 31,000 people) – April 2019
- More Calcium absorbed with more vitamin D – 6.7% more with 4000 IU – RCT March 2014
- Decrease Calcium and Increase Magnesium when increasing vitamin D
- Calcium supplements proven to NOT reduce fractures, but are proven to INCREASE heart problems – July 2015
- More than 1.4 grams of Calcium increased male death rate by 1.4 X – Sept 2018
- 10,000 IU of Vitamin D is too much if you also take Calcium supplements – RCT Sept 2018
- Calcium Essential to Limit Osteoporosis but Avoid Excess, Say Europeans - Nov 2017
- Hypercalcemia can result from excess Vitamin D (if not reduce Ca or increase water) Oct 2016
- Must balance co-factors when increasing vitamin D 500 Ca, 500 Mg - which has the following concept graph
Items in both categories Calcium and Vitamin K are listed here:
- Calcium and Vitamin K2 - many studies
- Excellent reviews of supplements at ConsumerLab
- Lowering Calcium Risk when having High Dose Vitamin D3 – Cawley Dec 2019
- Excess Calcium in critically ill patients taking 10,000 IU of vitamin D (solutions - Vitamin K, or Magnesium, or water) – Oct 2019
- Calcium Supplementation is OK provided you also take Vitamin K – Feb 2019
- Calcium supplements go to muscle, not bone, unless have enough Vitamin K – Feb 2019
- Drugs which create deficiencies in Vitamin D, Vitamin K, Magnesium, Zinc, Iron, etc. – Sept 2017
- Vitamin D Cofactors in a nutshell
- Vascular calcification greatly reduced by 3 per week 1000 ug of Vitamin K2 MK-7 – Dec 2013
- Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013
- Review of Micronutrients such as vitamin D for women and childhood – Aug 2013
- Healthy bones need Ca, Silicon, Vitamins B, C, D, and K – Dec 2012
- Interview of Vitamin K2 and Calcium Paradox author by Dr. Mercola – Dec 2012
- Vitamin K2 and the Calcium Paradox – 2012 book
- Low cost cofactors for vitamin D
- Postmenopausal women should supplement vitamins C D K and Calcium – June 2010
Items in both categories Calcium and Magnesium are listed here:
- Less Calcification if less Calcium, Vitamin K, Magnesium, etc. - many studies
- You are probably unaware that health needs a Ca-Mg ratio of 2 – Sept 2022
- Calcium to Magnesium Ratio - many studies
- COVID treatment patent applied for - using Rutin, Vitamin D, Vitamin C, Magnesium, etc. – April 2022
- Excellent reviews of supplements at ConsumerLab
- Increased dental decay if take Calcium without Magnesium – Feb 2020
- Off topic: Transcutaneous enhancers (DMSO, etc) for Vitamin D, Vitamin C, Resveratrol, Magnesium, etc.
- Colorectal Cancer risk increases 1.6 X if high Calcium, low Magnesium and a poor gene – Sept 2007
- Mineral adsorption and Vitamin D (Magnesium, Calcium, etc) - 2011
- Drugs which create deficiencies in Vitamin D, Vitamin K, Magnesium, Zinc, Iron, etc. – Sept 2017
- Natural variation in mineral content of a food is typically 3 to 1 – Nov 2016
- Interactions between Magnesium, Vitamin D, and Calcium – April 2016
- Is a health problem associated with Low vitamin D, Low Magnesium, or too much Calcium – Jan 2016
- Vitamin D - Comparing Symptoms of Hypercalcemia with Low Magnesium - Sept 2015
- Vitamin D Cofactors in a nutshell
- Vitamin D increases mineral availability which protect against toxic elements - July 2015
- Stronger bones after 3 generations of tap water (more Ca and Mg) vs bottled water – March 2015
- Magnesium may be more important to kids’ bone health than calcium – May 2013
- Calcium 2X of Magnesium seems good – China Feb 2013
- RDA upper limit etc for Vitamin D and Magnesium - Sept 2011
- Weight loss and Vitamin D, Calcium, and Magnesium
- Decrease Calcium and Increase Magnesium when increasing vitamin D
- 400 IU of vitamin D Magnesium and Calcium helped Twin bones – Feb 2011
- Low cost cofactors for vitamin D
- Constipation - Magnesium, Calcium and cofactors
- Calcium in food increased much more than Magnesium in recent decades April 2010
 Download the PDF from VitaminDWiki
Background
There are indications that an increased intake of calcium has a vitamin D sparing effect, which might be explained by a decreased catabolism of 25-hydroxyvitamin D (25(OH)D). However, there are only a few studies where this has been examined.Method
In the seventh survey of the Tromsø study, serum 25(OH)D and parathyroid hormone were measured, and questionnaires on calcium and vitamin D intakes filled in.Results
There were significant interactions between sex, calcium and vitamin D intakes regarding serum 25(OH)D level. The analyses were therefore done stratified. In males there was, regardless of vitamin D intake, a significant decrease in serum 25(OH)D with increasing calcium intake. The difference in serum 25(OH)D between those with the highest and lowest calcium intakes was approximately 10%. In the females, there was in subjects with low vitamin D intake (< 7 μg/d) a significant increase in serum 25(OH)D with increasing calcium intake, which could not be explained by secondary hyperparathyroidism. In females with higher vitamin D intakes, increasing calcium intake was associated with lower serum 25(OH)D levels.Conclusions
There is, at least in subjects with an adequate vitamin D intake, a negative association between calcium intake and serum 25(OH)D.2247 visitors, last modified 03 Nov, 2020,