Table of contents
- The effect of combined magnesium and vitamin D supplementation on vitamin D status, systemic inflammation, and blood pressure: A randomized double-blinded controlled trial
- VitaminDWiki - Hypertension category contains
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17 studies in both categories Hypertension and Intervention - VitaminDWiki -
9 studies in both categories Hypertension and Vitamin D Receptor - VitaminDWiki -
11 studies in both categories Hypertension and Magnesium
The effect of combined magnesium and vitamin D supplementation on vitamin D status, systemic inflammation, and blood pressure: A randomized double-blinded controlled trial
Nutrition. Jul-Aug 2022;99-100:111674. doi: 10.1016/j.nut.2022.111674
May M Cheung 1, Rosemary D Dall 2, Patricia A Shewokis 3, Asma Altasan 4, Stella L Volpe 5, Renee Amori 6, Harpreet Singh 7, Deeptha Sukumar 8Vitamin D levels raised by 6 ng when Mg added
Vitamin D + Mg reduced HT the most (Blurry Google Images)
Objective: Poor vitamin D and magnesium status is observed in individuals who are overweight and obese (Owt/Ob) and is often associated with a heightened risk of cardiovascular disease. Magnesium is a cofactor that assists vitamin D metabolism. We aimed to determine the efficacy of a combined magnesium and vitamin D regimen compared with vitamin D only on increasing serum 25-hydroxyvitamin D (25OHD) concentrations and the effects of these supplements on cardiometabolic outcomes.Methods: This 12-week double-blinded randomized controlled trial had three treatment arms: magnesium + vitamin D (MagD; 360 mg magnesium glycinate + 1000 IU vitamin D 3 × daily), vitamin D only (VitD; 1000 IU vitamin D 3 × daily), and placebo. A total of 95 Owt/Ob participants were randomized into one of these three study arms. Anthropometry, dietary intake, concentrations of serum 25OHD, serum parathyroid hormone (PTH), serum inflammatory markers, and blood pressure were obtained at baseline and week 12.
Results: The MagD group experienced the greatest increase in serum 25OHD concentrations (6.3 ± 8.36 ng/mL; P < 0.05). There was a decrease in systolic blood pressure (7.5 ± 8.26 mmHg; P < 0.05) for individuals who had a baseline systolic blood pressure of >132 mmHg in the MagD group. There were no statistically significant treatment effects on serum PTH concentrations and markers of inflammation.
Conclusions: A combined MagD treatment may be more effective in increasing serum 25OHD concentrations compared with VitD supplementation alone in Owt/Ob individuals.
VitaminDWiki - Hypertension category contains
164 items in the category HYPERTENSION see also
Overview Overview Hypertension and Vitamin D
Overview Cardiovascular and vitamin D
Overview Stroke and vitamin D
Incidence of 22 health problems related to vitamin D have doubled in a decade
Some interesting Hypertension studies- Hypertension risk decreased 10X by increasing vitamin D levels to more than 40 ng – Nov 2017
- COVID-19 deaths 4 to 7 X more likely if Diabetic, Hypertensive, or CVD - meta-analysis March 2020
- Magnesium reduces hypertension - FDA allows claim - Jan 2022
- Drug-resistant hypertension 3.5 X more likely if low vitamin D – March 2020
- High Blood Pressure reduced by Vitamin D supplementation in seniors and obese – meta-analysis May 2019
- Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014
- Hypertension is associated with low vitamin D in some groups – meta-analysis April 2015
- Off Topic – Hypertension in 42 percent of adults (new definition: 130 mm Hg) – Feb 2018
- Men aged 40-59 59%, age >60 75%: National Health and Nutrition Examination Survey, 2017–2018
VitaminDWiki -
17 studies in both categories Hypertension and Intervention This list is automatically updated
- Hypertension reduced by Magnesium plus 3,000 IU of vitamin D for 12 weeks – RCT July 2022
- A small amount of Vitamin D for a short time does not help (2800 IU, 8 weeks) – RCT Oct 2021
- Pulmonary Hypertension deaths prevented by 80 ng of Vitamin D (in rats) – July 2017
- Preeclampsia risk reduced 7X by 4,000 IU of Vitamin D daily – RCT March 2018
- Blood pressure reduced by monthly 100,000 IU of vitamin D in those who were deficient – RCT Oct 2017
- Preeclampsia recurrence reduced 2 X by 50,000 IU of vitamin D every two weeks – RCT July 2017
- Pulmonary hypertension reduced in some people with weekly 50,000 IU vitamin D for 3 months – 2016
- Preeclampsia risk reduced by higher levels of vitamin D (VDAART 4,400 IU) - RCT Nov 2016
- 2000 IU of vitamin D for just 2 weeks helped in many ways – RCT June 2016
- Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015
- Arterial stiffness reduced by a single dose of 100,000 IU of vitamin D – RCT Dec 2014
- Hypertension not reduced by adding vitamin D to patients who had enough vitamin D – RCT June 2014
- Hypertension (both systolic and diastolic) reduced with 2,000 IU of vitamin D – RCT June 2014
- Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014
- 3000 IU reduced hypertension for the vitamin D insufficient – RCT Aug 2012
- Hypertension reduced 6.8 mmHg with 3,000 IU of vitamin D daily – RCT May 2012
- Systolic blood pressure reduced by vitamin D (many studies)
VitaminDWiki -
9 studies in both categories Hypertension and Vitamin D Receptor A poor Receptor will restrict how much vitamin D actually gets to the cells
This list is automatically updated- 4 Cardiovascular diseases are associated with little vitamin D getting to cells – May 2023
- Health problems running in family may be due to poor vitamin D (hypertension, VDR in this case) Sept 2022
- Hypertension during pregnancy: low Vitamin D, poor Vit. D genes – June 2022
- Preeclampsia reduced by Vitamin D - many studies
- Hypertension risk increased 2.1 X if poor Vitamin D Receptor – Dec 2019
- Helicobacter pylori infection and low vitamin D – several studies
- Hypertension, Vitamin D, and Vitamin D Receptor – Aug 2019
- Preeclampsia 2X more likely if poor Vitamin D Receptor – April 2019
- Hypertension, Vitamin D Receptor, and FokI gene – Editorial Aug 2014
VitaminDWiki -
11 studies in both categories Hypertension and Magnesium This list is automatically updated
- Magnesium reduces hypertension - FDA allows claim - Jan 2022
- Hypertension reduced by Magnesium plus 3,000 IU of vitamin D for 12 weeks – RCT July 2022
- More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased) - March 2021
- Hypertension treatment needs at least 600 mg of Magnesium (49 trials) – Jan 2021
- The Role of Magnesium in the Pathogenesis of Metabolic Disorders – April 2022
- Reduce blood pressure by 9 mm with triple hypertensive drug or 19 mm with Magnesium – April 2018
- Hypertension nonconventional therapies: Magnesium, melatonin, Vitamin C, etc. – Jan 2018
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- Prehypertension risk is increased by 78% if low Magnesium – Aug 2015
- Preeclampsia inversely proportional to serum Magnesium – Oct 2014
- Hypertension 1.5X more likely if low level of Magnesium - Oct 2014
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