Effect of vitamin D3 supplementation on HIV-infected adults: a systematic review
- HIV category listing has
45 items along with related searches
- Overview HIV and vitamin D
- Use of Tenofovir disoproxil fumarate (Hepatitis-B, AIDS) requires more vitamin D – Sept 2018
- Treatment of HIV in youths helped by 7,000 IU of vitamin D – RCT July 2014
- 7000 IU of vitamin D restored most HIV youths to above 32 ng - RCT March 2014
- HIV interactions with low Vitamin D - May 2013
- HIV patients having EFC therapy were 3X more likely to have low vitamin D levels – Sept 2012
- perhaps the drug, rather than the HIV, lowers the vitamin D levels
- Blacks with HIV were 3.5X more likely to be vitamin D deficient than whites – May 2012
Items in both categories HIV and Non-daily intervention are listed here:
- HIV treatment augmented by high-dose vitamin D, daily or weekly – Dec 2021
- HIV therapy reduces Vitamin D levels, supplementation helps - Nov 2019
- HIV patients helped by monthly 120,000 IU of Vitamin D – RCT Oct 2017
- Vitamin D levels of HIV and non HIV equally restored with 50,000 IU twice a week - July 2015
- HIV – recommend 100,000 IU vitamin D monthly to get levels 30 ng – May 2013
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Nayra do Socorro Caldas Carvalho de Almeida Teixeira1, Beatriz de Mello Pereira1, Iara Katrynne Fonseca Oliveira1, Carlos Henrique Ribeiro Lima1, Cecilia Maria Resende Gongalves de Carvalho2, Ivone Freires de Oliveira Costa Nunes1, Dorcas Lamounier Costa3 and Adriana de Azevedo Paiva2
- 1 Graduate Program in Food and Nutrition. Universidade Federal do Piaui Brazil.
- 2 Nutrition Department. Universidade Federal do Piaui. Brazil. Mother and Child Health Department. Universidade Federal do Piaui. Brazil
Introduction: much evidence confirms that vitamin D may be associated with an improvement in CD4 cell counts in HIV-infected individuals, where antiretroviral therapy (ART) is used and associated with decreased 25(OH)D levels.
Objective: to carry out a systematic review on the effect of vitamin D supplementation on HIV-infected adult patients.
Methods: the research was conducted in the databases Science Direct, PubMed, BVS, Scielo Cochrane and Periods, from February to April 2018, with publication limit from 2000 to 2018, without restriction of gender, ethnicity and involving individuals with age older than 18 years. To evaluate the quality of the studies, we used the protocol Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) and the Jadad scale.
Results: the search initially resulted in 198 articles. After the selection process 5 articles were identified as eligible, where they highlight that vitamin D supplementation may be an associated and effective intervention to reduce hypovitaminosis. ART reduces vitamin D3 levels and changes its metabolism, being associated with the risk of mortality. However, adequate levels of 25(OH)D are positively associated with the number of CD4 + cells and the reduction of infection levels.
Conclusion: vitamin D supplementation promotes immune recovery. However, the cases analysed were few, insufficient to fully confirm the
Vitamin D. benefits and recommend supplementation. Therefore, intervention studies are needed to elucidate the role of vitamin D in human protection