Fibromyalgia benefits from transdermal magnesium chloride – Sept 2015

  • spray FibroFlex: a 31% magnesium chloride solution, water and “a proprietary blend of trace minerals on skin
  • apply four sprays per arm into the palm and rub onto one limb and repeat for each limb every 4 waking hours.
  • 22% of dropouts related to skin irritation.
VitaminDWiki

Both Magnesium and Vitamin D can be used internally and topically
   I use all 4: 1) Vit D internally, 3) Vit D topically,3) Mg internally, 4)Mg topically
I have used transdermal Magnesium Chloride for several years.
Relieves most muscle pain (exercise, back, sprain) in about 10 minutes
   It has also has eliminated osteoarthritis pain in my knees
I add Magnesium Chloride oil into a DMSO cream (Amazon $18) for quick penetration
   I have tried an assortment of DMSOs and MgCl, and now make my own MgCl oil from MgCl crystals
Usually just a single treatment of about 1/8 teaspoon is needed.
Rarely a second or third treatment is needed the same day to relive muscle pain
     Henry Lahore, admin of VitaminDWiki
Note - several friends are now using MgCl to greatly reduce their heart arrhythmias
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Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study.

J Integr Med. 2015 Sep;13(5):306-13. doi: 10.1016/S2095-4964(15)60195-9.
Engen DJ1, McAllister SJ2, Whipple MO2, Cha SS3, Dion LJ2, Vincent A2, Bauer BA2, Wahner-Roedler DL4.
1Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota 55905, USA.
2Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
3Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55905, USA.
4Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA; E-mail: wahnerroedler.dietlind@mayo.edu.

BACKGROUND:
Fibromyalgia is a syndrome characterized by chronic pain, fatigue, depression, and sleep disturbances. Its primary cause is unclear. Several studies have reported decreased intracellular magnesium levels in patients with fibromyalgia and have found negative correlation between magnesium levels and fibromyalgia symptoms.

OBJECTIVE:
To gather preliminary data on whether transdermal magnesium can improve quality of life for women who have fibromyalgia.

DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS:
This is a patient questionnaires and survey in a fibromyalgia clinic at a tertiary medical center. Forty female patients with the diagnosis of fibromyalgia were enrolled. Each participant was provided a spray bottle containing a transdermal magnesium chloride solution and asked to apply 4 sprays per limb twice daily for 4 weeks. Participants were asked to complete the Revised Fibromyalgia Impact Questionnaire, SF-36v2 Health Survey, and a quality-of-life analog scale at baseline, week 2, and week 4.

MAIN OUTCOME MEASURE:
Questionnaire and survey scores, evaluated through intent-to-treat and per-protocol analyses.

RESULTS:
Twenty-four patients completed the study (mean [SD] age, 57.2 [7.6] years; white, 95%; mean body mass index, 31.3 kg/m2). With intention-to-treat analysis, Revised Fibromyalgia Impact Questionnaire subscale and total scores were significantly improved at week 2 and week 4 (total score, P=0.001). Per-protocol analysis results were similar: all subscales of the Revised Fibromyalgia Impact Questionnaire were significantly improved at week 2 and week 4 (total score, P=0.001).

CONCLUSION:
This pilot study suggests that transdermal magnesium chloride applied on upper and lower limbs may be beneficial to patients with fibromyalgia.

TRIAL REGISTRATION: ClinicalTrials.gov.ldentifier NCT01968772.

PMID: 26343101

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