Understanding depression in type 2 diabetes: a biological approach in observational studies
F1000Research 2018, 7(F1000 Faculty Rev):1283 Last updated: 15 AUG 2018 [version 1; referees: 2 approved]
Thomas van Sloten1-3, Miranda Schram
Strangely the word vitamin does not occur even once in the PDF
- Depression 2X more common among diabetics, both associated with low vitamin D – 2014
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018 beck depression inventory (-2.8 vs. -0.9, P = 0.01),
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
- Hypothesis: Vitamin D is the link between Osteoporosis, Obesity, and Diabetes – April 2014
- Low vitamin D is associated with most types of depression: Seasonal Affective Disorder. manic depression, bipolar disorder, dysthymia, pregnancy, Seniors, Suicide
Items in both categories Diabetes and Depression are listed here:
- Depression more likely if low vitamin D (3.5 X prediabetic women in this case) – Oct 2022
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Depression twice as common in Diabetics (both have low vitamin D) – Aug 2018
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- ALL of the top 10 health problems of women are associated with low vitamin D
- Depression 2X more common among diabetics, both associated with low vitamin D – 2014
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
- Hypothesis non-severe depression and diabetes related by low vitamin D – June 2011
- Chicago Sun Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010
- Table of outcomes for seniors vs vitamin D level
Download the PDF from VitaminDWiki
Depression is twice as common in type 2 diabetes as in the general population and is associated with adverse health outcomes. Growing evidence suggest that type 2 diabetes and depression share biological mechanisms. This brief commentary discusses current understanding of shared biological pathways, focussing on hyperglycaemia, (micro)vascular dysfunction, and low-grade inflammation. Although there is accumulating evidence that these pathways are involved in the link between type 2 diabetes and depression, direct evidence of their temporal associations is lacking because of a paucity of longitudinal studies that focus on the pathobiology of both type 2 diabetes and depression.