Chronic Kidney Disease Patients need Vitamin K – Jan 2019

Vitamin K in Chronic Kidney Disease.

Nutrients. 2019 Jan 14;11(1). pii: E168. doi: 10.3390/nu11010168.
Cozzolino M1, Mangano M2, Galassi A3, Ciceri P4, Messa P5, Nigwekar S6.


Poor kidneys rarely get enough or the right form of vitamin D – Feb 2019

Items in both categories Kidney and Vitamin K are listed here:

Kidney category starts with

Kidney category listing has 221 items

see also Overview Kidney and vitamin D
Peritoneal dialysis in titles in VitaminDWiki (3 titles as of Oct 2021)
CKD or CHRONIC KIDNEY DISEASE in title of 65 pages as of Dec 2022

Calcitriol category listing has 56 items along with related searches

Overview Vitamin K and Vitamin D contains the following summary

Vitamin K2 is similar to D3 in many ways

  1. Both vitamins were initially confused with its lesser form (D2 ==> D3, K1 ==> K2)
  2. Both vitamins appear to influence health in large number of ways
  3. Both vitamins in the body are about 1/10 that of a century ago
    Example: Grass-fed beef has a lot more K2, D3, and Magnesium
  4. Need very little of both vitamins: <1 milligram daily
  5. When Vitamin D3 is increased, it appears that Vitamin K2 should also be increased
  6. Vitamin K2 understanding and research is about 20 years behind that of Vitamin D3
    One of the reasons: No simple blood test for K2 as of Jan 2020

 Download the PDF from VitaminDWiki

Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kidney disease (CKD) patients suffer from subclinical vitamin K deficiency, suggesting that this represents a population at risk for the biological consequences of poor vitamin K status. This deficiency might be caused by exhaustion of vitamin K due to its high requirements by vitamin K-dependent proteins to inhibit calcification.

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