Chronic kidney treatment by Vitamin D lacks consensus: type, how much – Sept 2018

Native vitamin D in pre-dialysis chronic kidney disease.

Nefrologia. 2018 Sep 28. pii: S0211-6995(18)30123-1. doi: 10.1016/j.nefro.2018.07.004

VitaminDWiki

Hypothesis: Magnesium might prevent and treat Chronic Kidney Disease – April 2018
Dialysis patients 23 percent more likely to live if had just 10 ng more Vitamin D – meta-analysis Feb 2018
UV is one of the ways to increase Vitamin D levels, even with poor kidney – Jan 2018
Standard oral vitamin D is not a good way to supplement if have Chronic Kidney Disease – March 2016 Promising other methods include: UV, topical, gut-friendly, injection, inhaled, sublingual, spray

Kidney category starts with

Kidney category listing has 220 items

see also Overview Kidney and vitamin D
Peritoneal dialysis in titles in VitaminDWiki (3 titles as of Oct 2021)
CKD or CHRONIC KIDNEY DISEASE in title of 65 pages as of Dec 2022

Calcitriol category listing has 56 items along with related searches

Overview Kidney and vitamin D contains the following summary

FACT: The Kidneys are not the primary way to activate vitamin D; the tissues are
FACT: When the Kidney has problems, there is less active vitamin D (Calcitriol) for the body
FACT: When the Kidney has problems, there is increased death due to many factors - many of which are associated with lack of Calcitriol
FACT: There are many ongoing intervention clinical trials trying to determine how much of what kind of vitamin D is needed to treat the problem
FACT: One Randomized Controlled Trial has proven that Vitamin D treats CKD
FACT: 38% of seniors have Chronic Kidney Disease and most are unaware of it CDC statistics 2020
FACT: Taking extra Vitamin D, in various forms, does not cause health problems - even if poor kidney
Suggestion: Increase vitamin D getting into body now - and increase co-factors so that the vitamin D can be better used
  Sun, UV lamp, Vitamin D supplement - probably > 5,000 IU,
Nanoemulstion vitamin D (inside cheek, topically) gets activated Vitamin D to the cells without the need for healthy kidney, liver, or intestine
Calcitriol - which bypasses the need for the kidney to activate vitamin D
  Problems with Calcitriol however: typically only lasts for a few hours, also, possible complications
    Update: Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012
Category Kidney and Vitamin D contains 220 items

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Cardoso MP1, Pereira LAL2.

1 Faculty of Medicine of University of Porto, Al. Prof. Hernâni Monteiro, 4200-451 Porto, Portugal. Electronic address: mariana.pinto.cardoso@gmail.com.
2 Institute of Investigation and Innovation in Health, University of Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Nephrology and Infeciology Group, INEB-National Institute of Biomedical Engineer, University of Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Department of Nephrology, São João Hospital Center, Al. Prof. Hernâni Monteiro, 4200-451 Porto, Portugal.

Chronic kidney disease patients have a high prevalence of vitamin D insufficiency/deficiency. Vitamin D deficiency has been associated with a variety of bone, metabolic and cardiovascular disorders. However, the role of native vitamin D supplementation (ergocalciferol, cholecalciferol or calcifediol) remains unclear in chronic kidney disease (CKD), particularly in the pre-dialytic phase. Several international guidelines have been developed on CKD-Mineral and Bone Disorder, but the optimal strategy for native vitamin D supplementation and its clinical benefit remains a subject of debate in the scientific community. This paper aims to review the available literature, including randomized clinical trials that evaluated the effects of native vitamin D supplementation on pre-dialysis CKD on biochemical and clinically relevant outcomes.