Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017

Aspirin Update March 2019%%%Daily Low-Dose Aspirin No Longer Recommended by Doctors, if You’re Healthy New York Times
The American College of Cardiology and American Heart Association released the new guidelines

Low Dose Aspirin and Omega 3 Fatty Acids in the Pro Resolving Pathway of Cardiovascular Disorders

Cardiology and Angiology: An International Journal. 6(4): 1-12, 2017; Article no.CA.36200 ISSN: 2347-520X, NLM ID: 101658392 DOI: 10.9734/CA/2017/36200
Jayavelan Ramkumar1 and Nidhi Sharma2
1 Department of Cardiothoracic Surgery, Sri Ramachandra Medical College and University, Chennai-600116, India.
2 Department of Obstetrics and Gynaecology, Saveetha Medical College, Saveetha University, Chennai-602105, India.

VitaminDWiki

Pages listed in BOTH the categories Omega-3 and Cardiovascular

Pages listed in BOTH the categories Vitamin K and Cardiovascular


 Download the PDF from VitaminDWiki

Newer mechanisms of action of Acetyl Salicylic acid have been discovered in proresolving pathway of various disorders. Omega 3 fatty acids are also involved in the synthesis of resolvins via an aspirin triggered pathway. The present review aims to discuss the role of recently discovered aspirin triggered lipoxins, resolvins, protectins, maresins in understanding the pathophysiology of endothelial dysfunction in various cardiovascular disorders, especially hypertension. The concept of aspirin triggered lipoxins (15-epi-LXA4 and 15-epi-LX4) counteracting the action of LTB 4PGE 2, and TXA2 is discussed. Aspirin triggered lipoxins also block the expression of IL-8 gene.
Aspirin is the only known NSAID to induce NO in a dose dependent manner. In this narrative review, we describe role of acetyl salicylic acid in the pro-resolution pathways that might prevent or reduce complications in patients with high blood pressure.

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