1.8 X more likely to have additional Dental Implant Failure if poor Vitamin D Receptor – Dec 2019

A complete physical mapping of the vitamin D receptor gene for dental implant loss: A pilot study.

Clin Oral Implants Res. 2019 Dec;30(12):1165-1178. doi: 10.1111/clr.13529
Munhoz Pereira T1, Alvim-Pereira F2, Kaiser Alvim-Pereira CC2, Ignácio SA1, Machado de Souza C1, Trevilatto PC1.

VitaminDWiki

The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019
Vitamin D Receptor Activation can be increased by any of: Resveratrol, Omega-3, Magnesium, Zinc. Quercetin, non-daily Vit D. Curcumin, intense exercise, Ginger, Essential oils, etc Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators

Items in both categories Dental and Vitamin D Receptor are listed here:

VitaminDWiki - Dental category contains

114 Dental items

Some Dental studies

Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
Caries (tooth decay) and Vitamin D - 23+ studies
Periodontitis reduced by Vitamin D - many studies
Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
7 Intervention AND Dental studies
18 items listed in BOTH Dental and Infant or Child
7 listed in BOTH Dental and Vitamin D Receptor

VitaminDWiki - DENTAL IMPLANT* in title

This list is automatcially updated

Items found: 5

Title		Modified
Dental implants 10 percent better with topical vitamin D (in dogs) – Sept 2015		31 Jan, 2022
More dental implant bone growth if high vitamin D (natural or supplement) – RCT Feb 2021		02 Feb, 2021
Dental implants more successful if higher level of vitamin D – Sept 2016		02 Feb, 2021
1.8 X more likely to have additional Dental Implant Failure if poor Vitamin D Receptor – Dec 2019		18 Dec, 2019
Dental implant failure 4 times more likely if low vitamin D (not statistically significant) – Sept 2016		16 Oct, 2016

Download the PDF from sci-hub via VitaminDWiki

OBJECTIVES:
The aim of this pilot case-control study was to investigate the association of clinical variables and genetic polymorphisms in the vitamin D receptor gene (VDR) with dental implant loss.

MATERIAL AND METHODS:
This study was carried out with 244 individuals with mean age 51.90 ± 11.28 (81 cases and 163 controls matched by age, sex, and smoking habit). Also, the clusterization phenomenon was investigated stratifying the sample into two groups: (a) 34 patients with multiple losses (presenting two or more lost implants) and (b) 210 without multiple losses (up to one implant loss). Sociodemographic, clinical, and periodontal parameters were analyzed. The tagSNPs in the VDR gene were analyzed by real-time PCR. Univariate and multivariate analyses were performed (p < .05).

RESULTS:
Edentulism, number of implants installed, and Gingival, Plaque, and Calculus Indexes were associated with implant loss in the univariate analysis. After the multivariate analysis, the allele G of rs3782905 in the recessive model, together with number of installed implants and Gingival Index, was associated with implant failure.

CONCLUSION:
It is suggested that the allele G of rs3782905 in the recessive model may be a new genetic risk marker for dental implant loss in patients who lost two or more dental implants. In addition, number of implants installed and Gingival Index were also associated. Replication is mandatory to confirm these findings, due to the modest sample size of this work.