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Recommend 100 IU of vitamin D per kg of infant - Poland July 2011

Vitamin d supplementation and status in infants: a prospective cohort observational study.

J Pediatr Gastroenterol Nutr. 2011 Jul;53(1):93-9.
Pludowski P, Socha P, Karczmarewicz E, Zagorecka E, Lukaszkiewicz J, Stolarczyk A, Piotrowska-Jastrzebska J, Kryskiewicz E, Lorenc RS, Socha J.
Department of Biochemistry and Experimental Medicine, Poland
Department of Gastroenterology, Hepatology and Immunology, Children's Memorial Health Institute, Aleja Dzieci Polskich, Poland
Department of Biochemistry and Clinical Chemistry, Warsaw Medical University, Banacha Warsaw, Poland
Department of Pediatrics and Auxiology, "Dr. L.Zamenhof" University Children's Hospital, Medical University of Bialystok, ul. Waszyngtona, Bialystok, Poland.

OBJECTIVE: Vitamin D status in infants depends on supplementation. We examined the vitamin D status in relation to supplementation dose and scheme in infants.

PATIENTS AND METHODS: One hundred thirty-four infants age 6 months and 98 infants age 12 months (drop out 27%) were investigated. Vitamin D intake (diet, supplements), anthropometry, and 25-hydroxyvitamin D (25-OHD) serum concentration at the 6th and 12th months were assessed.

RESULTS:Vitamin D intake of 1062 ± 694 IU at the 6th month was not different from that at the 12th month (937 ± 618 IU). Vitamin D intake expressed in international units per kilogram of body weight decreased from 141 ± 80 IU/kg at the 6th month to 93 ± 62 IU/kg at the 12th month (P < 0.0001), which was associated with a reduction in 25-OHD from 43 ± 20 ng/mL to 29 ± 12 ng/mL, respectively (P < 0.0001).

In the subgroup of everyday supplemented infants (n = 43), vitamin D intake decreased from 143 ± 88 IU/kg at the 6th month to 118 ± 60 IU/kg at the 12th month (P < 0.05), which coincided with a reduction of 25-OHD from 40 ± 19 ng/mL to 32 ± 13 ng/mL (P < 0.01).

In the subgroup with variable supplementation habits (n = 32), vitamin D intake decreased from 146 ± 79 IU/kg to 77 ± 56 IU/kg (P < 0.001), which was associated with a reduction of 25-OHD from 42 ± 21 ng/mL to 25 ± 8 ng/mL (P < 0.0001). 25-OHD concentration change between the 6th and the 12th months negatively correlated with the 25-OHD level assessed at the 6th month (r = -0.82; P < 0.0001).

CONCLUSIONS: Vitamin D supplementation of infants should consider their rapid body weight increment.
We postulate vitamin D daily dose close to 100 IU/kg body weight as favorable for infants up to age 12 months.

PMID: 21694542
 Download the PDF from VitaminDWiki


1000 IU per 25 lbs.jpg

NOTES

  • 1000 IU per 25 lbs (recommended by some in the US) is about 1% different than 100 IU/kg
  • The Red line is the average weight of children at that age.
  • This article recommends this amount up to age 12 months, others recommend it for up to age 12 years
  • Many Veterinary recommend this amount for cows, horses, etc. (file, not web page)

See also VitaminDWiki - Veterinary

See also VitaminDWiki

Fewer than 40% of infants got 400 IU of vitamin D,

A June 2010 study - MANY children do not even get 200 IU, and NONE of the children got more than 480 IU

from Dietary Guidelines for Americans vitamin D - June 2010

A Finland study tried 2,000 IU dose for 10,000 CHILDREN

They reported a significant decrease in type I diabetes decades later - NO toxicity, hypercalification, etc. etc.!

After infant stops drinking formula/milk, be sure to supplement with vitamin D - fruit juice is rarely fortified with vitamin D.

Note: that typically happens between age 1 and 3

Attached files

ID Name Comment Uploaded Size Downloads
11309 Poland 2011.pdf admin 31 Jan, 2019 23:09 470.50 Kb 65
575 weight vs age.png admin 23 Jun, 2011 22:25 46.62 Kb 932
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