Prevalence and Risk Factors for Hypovitaminosis D in Young Patients with Inflammatory Bowel Disease: A Retrospective Study
Pappa, Helen M; Langereis, Eveline J; Grand, Richard J; Gordon, Catherine M
Journal of Pediatric Gastroenterology & Nutrition: ACCEPTANCE, 21 May 2011, doi: 10.1097/MPG.0b013e3182250b3e
Short communication: PDF Only
Background and Aims: Vitamin D plays an important role in bone homeostasis. Children with inflammatory bowel disease (IBD) are known to have several risk factors for hypovitaminosis D. We aimed to report the prevalence of hypovitaminosis D in this population and risk factors associated with low serum twenty five hydroxy-vitamin D (25OHD) concentration in children with IBD.
Methods: Serum 25OHD concentration of 448 patients with IBD 8 to 22 yrs measured between January 2006 and January 2009 at our Center was recorded via retrospective chart review. Data collected included diagnosis (ulcerative colitis (UC), Crohn disease (CD) and indeterminate colitis (IC)), demographics, serum albumin concentration, erythrocyte sedimentation rate, vitamin D intake, season of measurement and height, and weight. Factors related to serum 25OHD concentration were identified with regression analysis.
Results: Serum 25OHD concentration <= 20 ng/mL (insufficiency) was identified in 64 patients (14.3%) and serum concentration <= 15 ng/mL (deficiency) in 26 (5.8%). Factors associated with lower serum 25OHD concentration were: winter and spring season, dark skin complexion, higher body mass index Z-score, lack of vitamin D supplementation and higher erythrocyte sedimentation rate.
Conclusion: Hypovitaminosis D is prevalent among children and youth, including patients with IBD. Risk factors for deficiency of this vitamin are similar to those in healthy children, with the addition of higher erythrocyte sedimentation rate. Both patients with UC and CD are at risk for hypovitaminosis D.
- All items in Gut and vitamin D
- Google Search for " inflammatory bowel disease" in VitaminDWiki 462 items Nov 2016
- IBD and Crohn but not Colitis associated with low vitamin D – May 2011
- IBD colorectal Cancer and vitamin D – Jan 2011
- Vitamin D might reduce military costs for UC and CD – June 2011
- Dogs – like humans – with IBD were low on vitamin D – July 2011
- Bio-emulsified drops doubled vitamin D levels – Dec 2010 especially good for people with gut problems
- Overview Deficiency of vitamin D shows the feedback problems of gut and vitamin DIBD UC and CD at risk of being vitamin D deficient – May 2011
4169 visitors, last modified 04 Nov, 2016,This page is in the following categories (# of items in each category)