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Vitamin D math mistakes made 7 years ago – K Baggerly 2016-2017

12 minute video, Nov 2016 @ American Public Health Association

Keith Baggerly is a Biostatistician, tenured professor and son of Carole Baggerly
kabagg at mdanderson.org

Mistake #1: % of cadavers with poor bones with 20-30 ng of vitamin D

They computed the ratio of bad bones with 20-30 ng vs all cadavers, rather than just those with 20-30 ng
If they had used the correct denominator the result would have been 28-30 ng, not 20 ng

Mistake #2: Not having enough data to conclude that >4,000 IU is too much (i.e. harm)

Chart did not have any error bars

This next chart shows the tiny differences

Two more mistakes

3) Institute of Medicine used data only for bone health, but the rest of the body needs higher levels
4) incorrectly estimated dose needed to get 97.5 % of population to a vitamin D level

His previously published study of the problem
 Download the PDF from VitaminDWiki

Sharing Scientific Data and Replicability, Keith Baggerly 45 minute video, March 2017

|Arthur M. Sackler Colloquia, Published on Mar 22, 2017
This talk was given by Keith Baggerly, MD Anderson Cancer Center as part of the National Academy of Sciences Arthur M. Sackler Colloquium on Reproducibility of Research: Issues and Proposed Remedies held in Washington, D.C. on March 8-10, 2017
Note: A Parathyroid Hormone analysis of 2016-2017 independently found that a vitamin D level of 31 ng is needed
Note: 97.5% of the population = 2 sigma of an ideal bell curve distribution (the actual distribution is a very distorted bell curve)

3,000 IU is needed to get 97.5% of the population to 30ng

Note: 3,000 IU daily ==> 42,000 IU every two weeks. which is very close to the 50,000 IU proposed by VitaminDWiki 3 years before
3,000 IU is 5X more than the 600 IU erroneous conclusion of the Institute of Medicine in 2010

Pregnant women in East Africa have vitamin D levels of about 60 ng

Yellow = pregnant women

Baggerly's are hoping to get signicant progress on correcting the error by the end of Sept 2017

See also VitaminDWiki

IoM error  8% not just 1% see http://is.gd/iomerror8

Note: Even if you have a good blood level of vitamin D,
    poor genes, low Magnesium, low Omega-3, etc restrict how much vitamin D actually gets to your cells

Vitamin D Receptor 160 studies found incidence of 16 health problems increased by at least 3X (as of Aug 2017)
Genetics category listing contains the following

326 articles in the Genetics category

see also

Vitamin D blood test misses a lot
in Visio for 2023

  • Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, and by 2017 was speculated to be 90%
  • Note: Good blood test results (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
  • A Vitamin D test in cells rather than blood was feasible (2017 personal communication)
  •    Commercially available 2019
    • However, test results would vary in each tissue due to multiple genes
  • Good clues that Vitamin D is being restricted from getting to the cells
    1) A vitamin D-related health problem runs in the family
    2) Slightly increasing Vitamin D shows benefits (even if conventional Vitamin D test shows an increase)
    3) Vitamin D Receptor test (<$30) scores are difficult to understand in 2016
    • easier to understand the VDR 23andMe test results analyzed by FoundMyFitness in 2018

    4) Back Pain

short URL = https://is.gd/VitDMath

Created by admin. Last Modification: Saturday March 16, 2019 16:16:57 GMT-0000 by admin. (Version 38)

Attached files

ID Name Comment Uploaded Size Downloads
8286 East Africa pregnant women.jpg admin 09 Aug, 2017 11:52 25.62 Kb 2101
8283 3,000 IU needed.jpg admin 09 Aug, 2017 11:26 31.57 Kb 2121
8282 Problems With the Serum RDA KB.pdf PDF 2016 admin 08 Aug, 2017 19:06 369.35 Kb 1038
8281 KB3.JPG admin 08 Aug, 2017 19:05 39.59 Kb 2123
8280 KB2.JPG admin 08 Aug, 2017 19:05 55.72 Kb 2204
8279 KB1.JPG admin 08 Aug, 2017 19:05 53.70 Kb 2388