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Vitamin D does not prevent all viral infections (enveloped virus not mentioned) – Jan 2019

The interplay between vitamin D and viral infections

Reviews in Medical Virology https://doi.org/10.1002/rmv.2032
Majid Teymoori‐Rad Fazel Shokri Vahid Salimi Sayed Mahdi Marashi

 Download the PDF from Sci-Hub via VitaminDWiki

The pleiotropic role of vitamin D has been explored over the past decades and there is compelling evidence for an epidemiological association between poor vitamin D status and a variety of diseases. While the potential anti‐viral effect of vitamin D has recently been described, the underlying mechanisms by which vitamin D deficiency could contribute to viral disease development remain poorly understood. The possible interactions between viral infections and vitamin D appear to be more complex than previously thought. Recent findings indicate a complex interplay between viral infections and vitamin D, including the induction of anti‐viral state, functional immunoregulatory features, interaction with cellular and viral factors, induction of autophagy and apoptosis, and genetic and epigenetic alterations. While crosstalk between vitamin D and intracellular signalling pathways may provide an essential modulatory effect on viral gene transcription, the immunomodulatory effect of vitamin D on viral infections appears to be transient. The interplay between viral infections and vitamin D remains an intriguing concept, and the global imprint that vitamin D can have on the immune signature in the context of viral infections is an area of growing interest.

Created by admin. Last Modification: Saturday January 12, 2019 16:34:39 GMT-0000 by admin. (Version 3)

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11194 Viral.pdf PDF 2019 admin 12 Jan, 2019 16:20 1.90 Mb 95
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