J Clin Res Pediatr Endocrinol. 2017 Sep 13. doi: 10.4274/jcrpe.4706. [Epub ahead of print]
Özdemir AA, Ercan Gündemir Y, Küçük M, Yıldıran Sarıca D, Elgörmüş Y, Çağ Y, Bilek G.
In 2005 Turkey reduced rickets by 60X after giving 400 IU of Vitamin D to every child
Now Turkey recommends that pregnant women take 1200 IU daily
Doubt that 1200 IU is enough to make a differance.in pregnancy or infant
The women in Turkey appear unwilling to pay for the vitamin D
12% used no Vitamin D
73% had supplemented with Vitamin D irregularly or used low doses (400 IU?)
14% got greater than 1,000 IU of vitamin D
Turkey sill considers 20 ng to provide an adequate level of Vitamin D
Middle Eastern women typically are in 2 categories for having low levels of vitamin D
- Dark Skin Dark skin births are much riskier due to lack of vitamin D
- Excessive clothing
- Burkas reduce vitamin D levels, which causes pregnancy problems – Oct 2015
- Saudi pregnancies – only 1 in 16 had even 20 nanograms of vitamin D – Nov 2015
- Middle East and Vitamin D category listing has
123 items along with related searches
- Much more than 2,000 IU of vitamin D is needed daily (Middle East studies agree) – meta-analysis Nov 2016
- Vitamin D given to ALL high schools girls in Iran – 75 percent deficiency dropped to 6 percent – April 2016
Healthy pregnancies need lots of vitamin D has the following summaryProblem
Reduces Evidence 0. Chance of not conceiving 3.4 times Observe 1. Miscarriage 2.5 times Observe 2. Pre-eclampsia 3.6 times RCT 3. Gestational Diabetes 3 times RCT 4. Good 2nd trimester sleep quality 3.5 times Observe 5. Premature birth 2 times RCT 6. C-section - unplanned 1.6 times Observe Stillbirth - OMEGA-3 4 times RCT - Omega-3 7. Depression AFTER pregnancy 1.4 times RCT 8. Small for Gestational Age 1.6 times meta-analysis 9. Infant height, weight, head size
within normal limits
RCT 10. Childhood Wheezing 1.3 times RCT 11. Additional child is Autistic 4 times Intervention 12.Young adult Multiple Sclerosis 1.9 times Observe 13. Preeclampsia in young adult 3.5 times RCT 14. Good motor skills @ age 3 1.4 times Observe 15. Childhood Mite allergy 5 times RCT 16. Childhood Respiratory Tract visits 2.5 times RCT
RCT = Randomized Controlled Trial
Vitamin D deficiency is a serious health problem although the improvement in socio-economic status in Turkey. The aim of this study was to evaluate the maternal vitamin D status and their effect on neonatal vitamin D status after support program for pregnant women and to detect risk factors for vitamin D deficiency in Bağcılar region in İstanbul.
A total of 97 pregnant women and 90 infants were included in this study between January and October 2016. The demographic data, risk factors and daily vitamin intake were recorded. We measured serum levels of vitamin D, calcium, phosphorus and alkaline phosphatase in mothers and their infants. The relationship between their vitamin D levels and risk factors was analyzed.
The mean vitamin D level for all women and all infants were found as 14.82 ±11.45 ng/ml and 13.16 ± 7.16 ng/ml, respectively. The number of mothers and infants were significantly higher in deficient group, and their mean vitamin D levels significantly lower (9.02 ± 1.34 ng/ml and 8.80 ± 1.06 ng/ml, respectively) (p < 0.001, p < 0.001).
The percent of pregnant women who have received 1000-1200 IU/day of vitamin D was only found as 14.4%. When the mother groups were evaluated in terms of risk factors, there were statistically differences in daily vitamin intake and clothing style (p < 0.001, p < 0.001).
Vitamin D deficiency in pregnant women and their infants is still a serious health problem in Turkey, although vitamin D support program has been launched for pregnant women.
PMID: 28901944 DOI: 10.4274/jcrpe.4706
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