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There are 2 concurrent pandemics – COVID-19 and Vitamin D deficiency – May 13, 2020


Br J Nutr. 2020 May 12;1-20. doi: 10.1017/S0007114520001749
Murat Kara 1, Timur Ekiz 2 timurekiz at gmail.com, Vincenzo Ricci 3, Özgür Kara 4, Ke-Vin Chang, Levent Özçakar 1
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World Health Organization announced the novel coronavirus disease (COVID-19) outbreak to be a global pandemic. The distribution of community outbreaks shows seasonal patterns along certain latitude, temperature, and humidity i.e. similar to the behavior of seasonal viral respiratory tract infections. COVID-19 displays significant spread in northern midlatitude countries with an average temperature of 5-11 °C and low humidity. Vitamin D deficiency has also been described as pandemic, especially in the Europe. Regardless of age, ethnicity, and latitude; recent data showed that 40% of the Europeans are vitamin D deficient (25(OH)D levels <50 nmol/L), and 13% are severely deficient (25(OH)D <30 nmol/L)
A quadratic relationship was found between the prevalences of vitamin D deficiency in most commonly affected countries by COVID-19 and the latitudes.
   Note: This equation does not appear to be in the text
Vitamin D deficiency is more common in the subtropical and midlatitude countries than the tropical and high latitude countries.
The most commonly affected countries with severe vitamin D deficiency are from the subtropical (Saudi Arabia; 46%, Qatar; 46%, Iran; 33.4%, Chile; 26.4%) and midlatitude (France; 27.3%, Portugal; 21.2% and Austria; 19.3%) regions.
Severe vitamin D deficiency was found to be nearly 0% in some high latitude countries (e.g. Norway, Finland, Sweden, Denmark and Netherlands).
Accordingly, we would like to call attention to the possible association between severe vitamin D deficiency and mortality pertaining to COVID-19. Given its rare side effects and relatively wide safety, prophylactic vitamin D supplementation and/or food fortification might reasonably serve as a very convenient adjuvant therapy for these two worldwide public health problems alike.


References

References

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COVID-19 treated by Vitamin D - studies, reports, videos (in VitaminDWiki)


Contents as of Sept 17:

  • 32 trial registrations, 1 trial result, 19 observations, 9 recommendations, 42 associations, 68 speculations, 23 videos


Top Vitamin D and COVID-19 recent updates

Search Google Scholar for COVID-19 Vitamin D 19,100 publications Sept 18, 2020


Intervention

Intervention Trial Summary Table
COVID-19 RCTs

Observe - Less likey to become infected

short URL to this section = https://is.gd/COVID_less

Observe - Reduced Severity/Death

Vitamin D Dosing Recommendations for COVID-19

Some people wanted improved immune systems, so took more vitamin D

COVID-19 associated with Low Vitamin D

Vitamin D levels are lower in those who test positive for COVID-19 -[doi:10.3390/nu12051359| Nutrients] May 09

    • Image
  • [https://articles.mercola.com/sites/articles/archive/2020/05/08/vitamin-d-level-correlated-to-covid19-outcomes.aspx?cid_source=dnl&cid_medium=email&cid_content=art1HL&cid=20200508Z1&et_cid=DM527863&et_rid=867359477 |Vitamin D Level Is Directly Correlated to COVID-19 Outcome] Mercola May 8
    • Overview of many studies and video by Ivor Cummins
  • [https://www.sciencedaily.com/releases/2020/05/200507131012.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fvitamin_d+%28Vitamin+D+News+--+ScienceDaily%29 |Vitamin D linked to low virus death rate in 20 countries in Europe] Science Daily May 7
  • [https://doi.org/10.1101/2020.05.01.20087965 |Evidence Supports a Causal Model for Vitamin D in COVID-19 Outcomes] May 6 preprint
    • Excellent extensive use of Causal Influence AI to discover associations.
    • I have suspected that Causal Influence could be much better, far lower cost, and faster than the use of RCTs
  • [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3586555|Evidence of Protective Role of Ultraviolet-B (UVB) Radiation in Reducing COVID-19 deaths] preprint May 7
    • "permanent unit increase in UVI is associated with a 2.2 % decline in daily growth rates of cumulative COVID-19 deaths [p < 0.01]
    • as well as a 1.9 % decline in the daily growth rates of CFR [p < 0.05]
    • 64 countries, 78 days, 6 UVI models
  • [https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3593258#.XrE0oF1wSjU.twitter |Vitamin D Level of Mild and Severe Elderly Cases of COVID-19: A Preliminary Report] May 5
    • 176 seniors in S. Asia - published in India
    • Image
  • Almost everyone with COVID-19 in a Louisiana ICU had low vitamin D – April 29, 2020
  • COVID-19 mortality rate highest North of 35 degrees latitude (Vitamin D) – April 20, 2020
  • COVID-19 was 19X more likely if low vitamin D (may be invalid data)– April 2020 Philippines
    • The raw data has strange gaps in the vitamin D levels
    • Image
  • Research Suggests a Link Between Vitamin D Deficiency and COVID-19 Deaths May 5
  • Indonesia preprint 13X if vitamin D insufficient,19X for patients who are vitamin D deficient.
    • VitaminDWiki has requested but has not yet access to the raw data
  • COVID-19 infections associated with very low vitamin D – Turin Italy – March 2020

Speculation

Image

Higher levels of vitamin D result in fewer COVID-19 problems

VIDEOS and PODCASTS


Groups which actively ignore Vitamin D possibility

  • The Wellcome-Gates COVID-19 Accelerator initiative expressly prohibits funding for Vitamins.


Why/How Vitamin D both treats and prevents virus

File not found.

Short URL for this section = https://is.gd/COVItaminD


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