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The relationship between Vitamin D and the respiratory system remains inconclusive – Jan 2016

Title = the first sentence in the study conclusion

A review of Vitamin D effects on common respiratory diseases: Asthma, chronic obstructive pulmonary disease, and tuberculosis

J Res Pharm Pract. 2016 Jan-Mar; 5(1): 7–15., doi: 10.4103/2279-042X.176542. PMCID: PMC4776550
Mohammad Esmaeil Hejazi,1 Faezeh Modarresi-Ghazani,2 and Taher Entezari-Maleki2

VitaminDWiki

Survey looked at articles up until July 2015.
   Many new studies since July 2015.

  • 46 articles: Vitamin D and asthma,
  • 11 articles Vitamin D and COPD,
  • 28 articles about Vitamin D and TB.

Breathing category in VitaminDWiki starts with the following

335 items in Breathing category

All of the studies in both Breathing and Intervention categories
  (give vitamin D and see what happens) are listed here:

All of the studies in both Breathing and Meta-analysis categories are listed here:


 Download the PDF from VitaminDWiki

Despite the classic role of Vitamin D in skeletal health, new aspects of Vitamin D have been discovered in tissues and organs other than bones. Epidemiological and observational studies demonstrate a link between Vitamin D deficiency and risk of developing respiratory diseases including asthma, chronic obstructive pulmonary disease (COPD), and tuberculosis (TB). To review the literature, we searched the terms “Vitamin D” (using the set operator) and “asthma,” “COPD” and “TB” in electronic databases, including PubMed/MEDLINE, Scopus, and Google Scholar until July 2015. Non-English articles or articles with unavailable full text were excluded. Both in vivo and in vitro studies were included. All the reviewed articles state that Vitamin D deficiency is very common among patients with respiratory diseases. The present data regarding Vitamin D and asthma is still controversial, but data about COPD and TB are more encouraging. The relevant studies have been conducted in different populations therefore it is not particularly possible to compare the data due to genetic variations. In order to point out a role for Vitamin D, large clinical trials with Vitamin D deficient subjects and sufficient Vitamin D supplementation are needed.

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