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The placenta and vitamin D – July 2012

Vitamin D, the placenta and pregnancy

Arch Biochem Biophys. 2012 Jul 1;523(1):37-47. doi: 10.1016/j.abb.2011.11.018. Epub 2011 Dec 2.
Liu NQ1, Hewison M.
1Department of Orthopaedic Surgery and Molecular Biology Institute, David Geffen School of Medicine at UCLA, 615 Charles E. Young Drive South, Los Angeles, CA 90095, USA.



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Impaired vitamin D status is common to many populations around the world. However, data suggest that this is a particular problem for specific groups such as pregnant women. This has raised important questions concerning the physiological and clinical impact of low vitamin D levels during pregnancy, with implications for classical skeletal functions of vitamin D, as well as its diverse non-classical actions. The current review will discuss this with specific emphasis on the classical calciotropic effects of vitamin D as well as the less well established immunological functions of vitamin D that may influence pregnancy outcome. The review also describes the pathways that are required for metabolism and function of vitamin D, and the various clinical complications that have been linked to impaired vitamin D status during pregnancy.

Copyright © 2011 Elsevier Inc. All rights reserved.

PMID: 22155151


See also VitaminDWiki

Different forms of vitamin D get thru the placenta and the breast
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click on image for details

Vitamin D Global Perspective - Holick June 2013 has the following chart
Lactation and Pregnancy @ /is.gd/Holick613

See also web

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Attached files

ID Name Comment Uploaded Size Downloads
6632 Week 4 to 10.jpg admin 02 May, 2016 48.63 Kb 1160
6631 Placenta Roth caption.jpg admin 02 May, 2016 47.12 Kb 1265
6630 Placenta Roth.jpg admin 02 May, 2016 64.38 Kb 3047