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Toggle Health Problems and D

Take vitamin D3 daily, weekly, or bi-weekly


Notional chart for Vitamin D supplementation for levels < 30 nanograms
see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=2475

Annual = Not good

During the past decade research studies have found that annual doses of vitamin D do not provide much benefit.
There are far fewer studies publishing results with annual doses.
Mostly the studies being published since 2010 are ones which were started many years ago.
We are unaware of any new Clinical Trials using annual doses
Sometimes annual doses have actually ended up causing problems - such as more falls.
Imagine the consequences of taking years worth of any food, supplement, or drug in a single day:
    such as: salt, water, iodine, aspirin, sugar, wheat, vitamin A, etc, etc.
Vitamin D is perhaps the only item for which taking the annual amount in a single day will not cause a call to 911 or immediate death

Quarterly = OK for some

Quarterly doses of vitamin D result in significant variations in blood levels of vitamin D - which stresses the body.
It appears, however, that the benefits of vitamin D outweigh the stresses of quarterly dosing.

Monthly = OK for most

The half-life for vitamin D for most people is approximately 1 month.
So, for most people, taking vitamin D monthly will result in a blood level of vitamin D which drops perhaps 30% by the end of the month
This variation results in some stress on the body.
Evolution has created bodies which typically experience even larger summer-winter changes in vitamin D levels
Note: there is some thought that the body needs to have variation in the vitamin D level - so should not keep it at a constant level all year long

The half life of vitamin D appears to be about a week for high level of vitamin D

Thus monthly doses of vitamin D appears to be NOT appropriate for people with vitamin D levels higher than 50ng/ml

Weekly = Great for most

Virtually everyone can take vitamin D weekly, say on Saturday, without any problems.
Note: Should probably take vitamin D co-factors more frequently.
The body cannot take a whole weeks worth at a time and the body does not store some of the co-factors very well.


222+ VitaminDWiki pages with WEEKLY OR BIWEEKLY in the title

This list is automatically updated

Items found: 221
Title Modified
Vitamin d levels were restored from hemodialysis by 70,000 IU weekly total in 4 weeks - Feb 2024 25 Feb, 2024
Vertigo incidence reduced 40% by just 7,000 IU Vitamin D given weekly - RCT Feb 2024 22 Feb, 2024
Following Bariatric surgery, weekly 50,000 IU of standard Vitamin D is not enough – Jan 2024 12 Jan, 2024
Vitamin D response in post-menopausal women: weekly better than monthly, notice benefit in 3 months – Jan 2021 23 Dec, 2023
Take 50,000 IU of Vitamin D weekly for 2-4 months, then get a test - Dec 2021 19 Dec, 2023
Consensus: 60,000 IU of Vitamin D weekly for 2-6 months can fight COVID, etc, – India April 2022 13 Oct, 2023
Simple vitamin D supplementation - daily, weekly, or monthly - Sept 2023 04 Oct, 2023
Vitamin D given daily, weekly, or monthly has similar response (116 RCTs) – meta-analysis Aug 2023 02 Oct, 2023
Muscles improved in women with 50,000 IU vitamin D weekly (8 weeks) plus daily Magnesium – RCT Sept 2020 16 Sep, 2023
Venous ulcers healed 4X faster with weekly 50,000 IU vitamin D – RCT Oct 2012 08 Sep, 2023
Senior cognition improved in 4 ways by Vitamin D (50,000 IU weekly for 8 weeks) – Sept 2023 06 Sep, 2023
Chronic Periodontitis reduced by Vitamin D (60,000 IU weekly for 8 weeks) – RCT July 2023 01 Sep, 2023
Pain relieved by Vitamin D if trial lasted more than 5 months (endometriosis, 50K weekly for 12 months) – Aug 2023 30 Aug, 2023
Type 2 Diabetes treated by Vitamin D (often 50,000 IU weekly) – meta-analysis July 2023 21 Aug, 2023
IBS reduced by 50,000 IU of Vitamin D (weekly or bi-weekly) – Meta-analysis July 2023 16 Aug, 2023
Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT Aug 2023 22 Jul, 2023
Take vitamin D3 daily, weekly, or bi-weekly 16 Jul, 2023
Menstrual pain reduced by weekly 50,000 IU of Vitamin D – meta-analysis June 2023 15 Jul, 2023
Multiple Sclerosis fatigue reduced by weekly Vitamin D (50,000 IU) – June 2023 15 Jul, 2023
60,000 IU vitamin D weekly with daily Calcium was safe but not enough in the winter – 2012 13 Jul, 2023
Cognition improved in 5 ways after Vitamin D increased to 32 ng (50,000 weekly) – June 2023 03 Jul, 2023
Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT July 2023 18 Jun, 2023
Mild Obstructive Sleep Apnea decreased by 50,000 IU weekly vitamin D – June 2021 20 May, 2023
Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT May 2023 20 May, 2023
Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding) 18 Apr, 2023
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and charts - March 2023 02 Apr, 2023
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and transcript - March 2023 01 Apr, 2023
thru weekly - looks good 04 Mar, 2023
Urinary Incontinence reduced by 50,000 IU of vitamin D weekly (details behind paywall) – RCT Feb 2023 24 Feb, 2023
Gut microbiome massively changed by weekly vitamin D – July 2015 19 Jan, 2023
Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022 22 Dec, 2022
50,000 IU Vitamin D weekly is often recommended 30 Nov, 2022
ADHD significantly treated by daily Magnesium plus weekly Vitamin D – RCT April 2021 30 Nov, 2022
Increase infant Vitamin D: forification, daily, weekly, monthly, breast milk - Review June 2022 07 Nov, 2022
50,000 weekly increased vitamin D levels in breast cancer patients – Mar 2011 06 Nov, 2022
Bone biomarkers increased equally by daily, weekly, or monthly Vitamin D (CKD in children in this case) – Nov 2022 02 Nov, 2022
COVID in hospital fought by Vitamin D (25,000 IU daily for 4 days, then 25K weekly) - RCT – July 2022 02 Oct, 2022
50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT May 2022 11 Jun, 2022
HIV treatment augmented by high-dose vitamin D, daily or weekly – Dec 2021 30 Jan, 2022
Poor odor detection if low Vitamin D, better after 50,000 IU weekly - July 2021 23 Jan, 2022
Several smoking problems treated by Vitamin D (bi-weekly, 50,000 IU) - RCT Dec 2021 29 Dec, 2021
Vitamin D proposed to fight COVID - up to 50K weekly – Jan 2021 16 Dec, 2021
Most Diabetics getting 40,000 IU of vitamin D weekly did not get to 30 ng (needed gut-friendly form) - RCT June 2020 30 Nov, 2021
Non-Alcoholic Fatty Liver Disease (NAFLD) treated by Vitamin D (20,000 IU weekly after loading dose) – RCT June 2016 05 Oct, 2021
50,000 IU Vitamin D weekly was the most popular for Breast Cancer - May 2020 30 Aug, 2021
Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021 19 Aug, 2021
Weekly Vitamin D plus daily Magnesium is great (reduced depression in obese women in this case) – July 2021 13 Aug, 2021
Vitamin D for infections and COVID (50,000 IU weekly for 3 months) – July 2021 02 Aug, 2021
Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019 25 Jul, 2021
Children's Cancer hospital now testing vitamin D frequently and supplementing weekly – July 2021 22 Jul, 2021
Pain reduced by Vitamin D (60K weekly, then monthly) plus daily Calcium in 3 months – May 2021 16 Jul, 2021
Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019 09 Jul, 2021
Cognitive function of adult women improved in 3 months of 50,000 IU weekly Vitamin D – Jan 2019 09 Jul, 2021
Infant Respiratory Infections not reduced by mothers taking small amount of vitamin D (28,000 weekly)– RCT July 2021 03 Jul, 2021
Immune systems helped by 50,000 IU of vitamin D (weekly for 3 months) – May 2021 03 Jun, 2021
Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019 25 May, 2021
54 genes significantly affected by Vitamin D (50,000 IU weekly for 12 weeks) – May 2021 12 May, 2021
Depression treated by 50K IU Vitamin D weekly (but not 1,000 IU daily) – meta-analysis Jan 2021 25 Apr, 2021
Elite sports teams adding 5,000 IU of vitamin D weekly did not see much benefit (no surprise) – April 2021 15 Apr, 2021
Stroke patients getting weekly 50,000 IU Vitamin D did better – trial March 2021 12 Mar, 2021
Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021 23 Feb, 2021
Weekly 50,000 IU was the most succesful way to restore vitamin D levels (football) - Aug 2020 08 Feb, 2021
Response to weekly Calcifediol in 4 months - RCT Aug 2022 03 Feb, 2021
Endometriosis treated by Vitamin D (50,000 IU bi-weekly) – RCT Jan 2021 30 Jan, 2021
Weekly response to semi-activated vitamin D slightly better than standard – RCT Nov 2019 21 Jan, 2021
Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015 14 Jan, 2021
Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination 27 Dec, 2020
Trial: Can 50,000 IU of Vitamin D weekly help with Breast Cancer Chemotherapy - Early 2021 21 Dec, 2020
Rational approach to COVID-19: 50k-100k of Vitamin D weekly – Dec 2020 20 Dec, 2020
A call to action: Vitamin D for hip fracture (50,000 weekly for 8 weeks, then bi-weekly – Holick July 2020 11 Dec, 2020
50,000 IU vitamin D weekly to avoid Osteroporosis after Breast Cancer - May 2020 26 Nov, 2020
BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT Nov 2020 21 Nov, 2020
60,000 IU dose of VItamin D (weekly, monthly) is popular in India 17 Nov, 2020
Taking 25-Hydroxy vitamin D3 weekly was patented in 2010 17 Oct, 2020
Semi-activated Vitamin D given weekly (used by Spanish COVID-19 trial) – US patent application Sept 2020 23 Sep, 2020
In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024 14 Sep, 2020
Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020 27 Aug, 2020
Childhood colds reduced 25 percent by weekly Vitamin D – RCT Jan 2019 19 Jul, 2020
Weekly oral Vitamin D recommended before surgery (Bariatric in this case) – RCT June 2019 19 Jul, 2020
Diabetic inflammation reduced by Vitamin D (30,000 IU weekly) – RCT July 2020 09 Jul, 2020
Weekly 50,000 IU of vitamin D is again found to be good – RCT May 2020 27 May, 2020
COVID-19 might be prevented in 2 months by 50,000 IU weekly – May 12, 2020 12 May, 2020
IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020 25 Mar, 2020
50,000 IU Vitamin D weekly provided enough benefit for combat sport athletes – March 2020 21 Mar, 2020
COPD trial to use 80,000 IU of vitamin D weekly – RCT 2021 19 Mar, 2020
Response by obese to weekly 50,000 IU of Vitamin D – May 2018 12 Feb, 2020
Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT Feb 2019 18 Jan, 2020
20,000 IU of Vitamin D weekly gave many benefits – RCT Aug 2019 17 Jan, 2020
Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023 16 Jan, 2020
Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs 25 Dec, 2019
Obese taking 50,000 IU of vitamin D weekly lost more weight (again) – RCT Dec 2019 25 Dec, 2019
Muscles not improved by just Vitamin D weekly (also need exercise) – Dec 2019 17 Dec, 2019
General Anxiety Disorder treated by weekly Vitamin D (50,000 IU -Omega-3, Mg also help) – Sept 2019 09 Dec, 2019
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019 19 Oct, 2019
Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019 17 Oct, 2019
Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT May 2019 10 Sep, 2019
Obese responded to weekly vitamin D better than non-obese – RCT March 2018 22 Aug, 2019
Severely Obese not helped much by 50,000 IU of vitamin D weekly for 8 weeks – RCT June 2019 21 Aug, 2019
Athletes helped by weekly 50,000 IU Vitamin D – RCT Aug 2019 10 Aug, 2019
Hay Fever treated by Vitamin D (50,000 IU weekly) – RCT July 2019 02 Aug, 2019
Statin pain eliminated by 7100 IU vitamin D (50000 IU weekly) – July 2011 21 Jul, 2019
Vitamin D less costly if give 100,000 IU monthly (but 50,000 IU biweekly should save more money) – July 2019 16 Jul, 2019
Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT Dec 2018 07 Jul, 2019
Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT – June 2019 01 Jul, 2019
100,000 IU Vitamin D weekly for 4 weeks is safe and effective for children – May 2019 14 Jun, 2019
PMS in teens reduced 3X by 50,000 IU vitamin D weekly – Jan 2018 23 Mar, 2019
Weekly Vitamin D to mother after birth much better than daily - RCT Aug 2018 11 Mar, 2019
Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT Feb 2019 21 Feb, 2019
Poor Vitamin D binding had 30 percent less response to Vitamin D (50,000 IU weekly) – Feb 2019 04 Feb, 2019
Doctor prescribed 200,000 IU Vitamin D2 weekly during pregnancy (wrong type, far too much) – Jan 2019 04 Jan, 2019
Ulcerative Colitis inflammation treated by weekly vitamin D (40,000 IU) – July 2018 21 Dec, 2018
Prediabetics not helped by weekly vitamin D (perhaps D2) – RCT Oct 2013 09 Dec, 2018
Depression probably treated by bi-weekly 50,000 IU of vitamin D - RCT 2020 05 Dec, 2018
50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014 24 Nov, 2018
Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018 21 Nov, 2018
Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019 17 Nov, 2018
Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017 02 Nov, 2018
Respiratory Virus risk reduced 35 percent by Vitamin D (14,000 IU weekly) – RCT Oct 2018 18 Oct, 2018
Depression in seniors treated by weekly 50,000 IU of vitamin D – RCT Sept 2018 15 Oct, 2018
Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT Sept 2018 10 Sep, 2018
Vitamin D dosing - weekly may be better than daily – video Aug 2018 02 Sep, 2018
50,000 IU of Vitamin D weekly for 9 weeks did not improve CVD – Aug 2018 28 Aug, 2018
Vitamin D given weekly better than daily (Nursing home, 5,600 IU weekly) – Aug 2018 07 Aug, 2018
Multiple Sclerosis treated by 50,000 IU Vitamin D bi-weekly plus Omega-3 – RCT July 2018 06 Jul, 2018
Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018 23 Jun, 2018
Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT May 2018 17 May, 2018
Vitamin D weekly supplementation (Spinal Cord Injury athletes) increased handgrip strength – May 2018 15 May, 2018
Weekly dosing of vitamin D is far better than single large dose (chronic liver, children) – March 2018 05 Mar, 2018
Pain not relieved by monthly 100,000 IU of vitamin D (need 50,000 IU weekly) – RCT Feb 2018 02 Mar, 2018
35,000 IU vitamin D weekly during 3rd quarter pregnancy – RCT March 2013 16 Feb, 2018
Elite Athletes do well with weekly 35,000 IU of Vitamin D – RCT Feb 2017 16 Feb, 2018
Cystic Fibrosis got some benefit from 50,000 IU of vitamin D weekly (need gut-friendly form) – Feb 2018 03 Feb, 2018
600,000 IU of vitamin D – 42 ng at 3 months for 1 inj, 3 inj, oral monthly, oral weekly - Oct 2017 15 Jan, 2018
Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT Nov 2017 18 Nov, 2017
Vitamin D toxicity problems from 600,000 IU weekly for 6 weeks – July 2017 30 Oct, 2017
Probably Fractures of the Tibia can be healed with 100,000 IU of vitamin D weekly – RCT 2023 23 Oct, 2017
Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019 23 Oct, 2017
Perhaps fewer bone non-unions with 100,000 IU weekly of vitamin D – RCT 2018 23 Oct, 2017
More than 5X increase in activation of scores of genes for women with Vitamin D (20,000 IU weekly) RCT Oct 2017 01 Oct, 2017
Vitamin D – 91 percent safely got above 30 ng in 2 months with weekly 30,000 IU – Aug 2017 16 Sep, 2017
Speculation – Weekly vitamin D dose will be better than daily if poor Receptor 12 Sep, 2017
Dry eye decreased with weekly 50,000 IU vitamin D injection for 8 weeks – Sept 2017 07 Sep, 2017
Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017 01 Sep, 2017
Knee osteoarthritis helped by vitamin D2 (40,000 IU weekly raised 57 % above 30 ng) June 2017 29 Jul, 2017
Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017 27 Jul, 2017
Cervical lesions (precancerous, identified by pap smear) treated by bi-weekly 50,000 IU of vitamin D – RCT Feb 2017 22 Jul, 2017
Statin-induced Myalgias corrected with 100000 weekly Vitamin D2 20 Jul, 2017
7100 IU (50000 weekly) got most women to 30 ng of vitamin D - Aug 2012 20 Jul, 2017
Vitamin D daily or weekly dosing resulted in similar response -RCT Jan 2016 20 Jul, 2017
Knee osteoarthritis treated with vitamin D, weekly 50,000 IU – May 2015 20 Jul, 2017
Weekly pizza fortified with 28,000 IU raised Vitamin D by 30 nanograms – RCT Aug 2015 20 Jul, 2017
50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013 20 Jul, 2017
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – Nov 2016 27 Jun, 2017
50,000 IU of vitamin D weekly (D3 or D2) got two thirds of cystic fibrosis patients to 30 nanograms – RCT July 2015 22 Apr, 2017
Optimal vitamin D supplementation strategies (D3 - weekly or monthly) – Feb 2017 02 Mar, 2017
50,000 IU vitamin D weekly is safe and effective for Primary Hyperparathyroidism – Jan 2013 23 Jan, 2017
Pulmonary hypertension reduced in some people with weekly 50,000 IU vitamin D for 3 months – 2016 16 Jan, 2017
2900 IU of vitamin D (20000 weekly) kept levels above 20 ng during the winter – Aug 2012 10 Jan, 2017
Chronic Back Pain relieved by weekly 60,000 IU of vitamin D – Jan 2017 10 Jan, 2017
Vitamin D injection lasts longer and has bigger response than weekly oral – Jan 2017 24 Dec, 2016
Juvenile Lupus fatigue reduced by vitamin D ( 50,000 IU weekly for 6 months) – RCT May 2015 24 Nov, 2016
Chikungunya virus arthritis pain reduced by weekly 60,000 IU vitamin D – Sept 2016 29 Sep, 2016
Diabetes not treated by 28,000 IU of weekly vitamin D (proven again) – RCT Sept 2016 26 Sep, 2016
7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease – July 2012 21 Sep, 2016
Graph of weekly response to monthly vitamin D supplementation – Aug 2015 17 Sep, 2016
5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT Dec 2015 06 Aug, 2016
Pregnancy – adding 35,000 IU Vitamin D weekly was nice, but not enough – RCT April 2016 23 Jul, 2016
Nursing home residents need Vitamin D 4,000 IU daily or 50,000 IU weekly – Jan 2016 25 May, 2016
IBS quality of life improved by vitamin D (50,000 IU weekly) – RCT May 2016 17 May, 2016
Prenatal Vitamin D (35,000 weekly) resulted in 1 cm taller infants at age 1 year – RCT Aug 2013 30 Apr, 2016
Prenatal Vitamin D (35,000 weekly, 3rd trimester) resulted in 1 cm taller infants at age 1 year – RCT Aug 2013 30 Apr, 2016
Prediabetics not helped by 50,000 IU of vitamin D weekly and Calcium– Jan 2013 03 Apr, 2016
Omega-3 weekly is more bio-available than daily (rat study) – July 2015 24 Feb, 2016
Pain of Diabetic Neuropathy reduced with weekly 50,000 IU vitamin D– CT Feb 2015 22 Oct, 2015
Vitamin D loading dose then weekly 50,000 IU not help (COPD) if very deficient – Oct 2015 16 Oct, 2015
Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015 15 Oct, 2015
Vitamin D is very important during pregnancy – 4,000 daily or 50,000 weekly - review Jan 2015 02 Oct, 2015
Hives treatment augmented by 60,000 IU Vitamin D weekly – RCT June 2015 22 Aug, 2015
No multiple sclerosis relapses during pregnancy if 50,000 IU of Vitamin D weekly – RCT April 2015 21 Jun, 2015
Near the end of pregnancy 50,000 IU vitamin D weekly was great – RCT April 2013 08 Jun, 2015
Respiratory infections (RTI) cut in half by 20,000 IU weekly vitamin D if initially deficient – RCT March 2015 18 Apr, 2015
Hemodialysis not helped by weekly vitamin D2 – RCT April 2015 08 Apr, 2015
Pregnant mothers in Quatar needed more than weekly 50,000 IU Vitamin D – Nov 2013 28 Mar, 2015
Peripheral Neuropathy in type II Diabetes reduced a bit by 50,000 IU weekly of vitamin D – RCT Feb 2015 28 Mar, 2015
Infants getting 1400 IU vitamin D weekly grew better – RCT May 2011 16 Mar, 2015
Response and adverse effects of 20,000 and 30,000 IU Vitamin D weekly - Feb 2015 09 Mar, 2015
25,0000 IU vitamin D weekly only raised 60 percent on hemodialysis above 30 ng – Nov 2014 13 Jan, 2015
Fraser Health in Canada will be giving 20000 IU vitamin D weekly to reduce falls – Nov 2011 07 Jan, 2015
Nursing home – 5600 IU vitamin D capsules weekly resulted in most being above 20 ng – Sept 2014 29 Dec, 2014
Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014 22 Nov, 2014
Diabetes treated by 50,000 IU of vitamin D weekly with 1 g Calcium daily – RCT July 2014 14 Sep, 2014
Vitamin D levels of seniors restored with 50,000 IU weekly for 8 weeks – April 2014 01 Sep, 2014
Vitamin D toxicity after 4 months of weekly 600,000 IU – 2012 29 Aug, 2014
7 improvements in lives of veterans with chronic pain with 50,000 IU vitamin D weekly – June 2012 20 Aug, 2014
70 percent of some skin problems resolved with 7100 IU vitamin D (50000 weekly) – Jan 2011 13 Aug, 2014
Asthma reduced by weekly 50,000 IU of vitamin D – RCT Aug 2014 03 Aug, 2014
20,000 IU weekly did not get 43 percent of Scottish Cancer patients to a level of 30 ng of vitamin D – April 2014 29 Jul, 2014
Obese children probably need more than 25,000 IU of vitamin D weekly – July 2014 18 Jul, 2014
Asthma is not treated by weekly 14,000 IU of vitamin D (proven yet again) July 2014 02 Jul, 2014
Optic neuritis progession into Multiple Sclerosis reduced 68 percent by 50,000 IU of vitamin D weekly 08 May, 2014
Statin-induced Myalgias corrected with 100000 weekly Vitamin D 04 May, 2014
COPD helped by weekly 50,000 IU Vitamin D – Aug 2013 03 May, 2014
Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014 10 Apr, 2014
Vitamin D update – 40-60 ng ideal, 50K biweekly maintenance – Jan 2014 24 Mar, 2014
Rickets prevented by single injection of vitamin D or weekly supplementation – RCT Jan 2014 24 Jan, 2014
7100 IU vitamin D (50,000 weekly) significantly reduced fibromyalgia – 2009 20 Jan, 2014
Need to adjust cofactors if take 50,000 IU of vitamin D weekly – Nov 2013 12 Jan, 2014
Chronic Fatigue Syndrome reduced with 25,000 IU of vitamin D weekly – June 2013 22 Nov, 2013
50,000 IU vitamin D weekly increased levels by 52 ng normally, but only 28 ng if obese – Oct 2013 13 Nov, 2013
40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008 09 Nov, 2013
Weekly cottage cheese associated with 1ng more vitamin D in blood (surprise) – Nov 2013 06 Nov, 2013
60,000 IU vitamin D weekly for 3 months lasts for another 3 months - April 2013 14 Jul, 2013
Vitamin D2 did not help Lupus (no surprise, D2 was given weekly) – June 2013 01 Jun, 2013
Insulin resistance helped with 50000 IU of vitamin D weekly – Feb 2013 11 Mar, 2013
Vitamin D deficiency somewhat treated with weekly 50000 IU Vitamin D2 – Sept 2012 10 Mar, 2013
Esophageal cancer clinical trial to see if 50000 IU vitamin D weekly well help – Oct 2010 10 Nov, 2012
50000 IU vitamin D2 weekly helped blacks with heart problems – Feb 2011 10 Nov, 2012
Weekly UV almost doubled elderly Vitamin D levels – Dec 2010 22 Aug, 2012
Dark skinned obese not helped much by weekly 50000 IU dose of vitamin D – May 2011 23 Dec, 2011
Fibromalgia reduced with 50,000 IU weekly vitamin D2 – Sept 2011 14 Dec, 2011
50,000 IU vitamin D suggested to prevent osteoporosis (weekly then monthly)– April 2019 No value for &#039;modification_date_major&#039;

Infrequent dosing provides higher Vitamin D gradient

Higher gradient (steeper slide) resulting from infrequent dosing results in more Vitamin D getting into the cells.
Note: Virtually all cells of the body can utilize/activate Vitamin D, no liver or kidney needed
Image

 

Daily: Can be this often, but it is not necessary.

Since most people take their pills on a daily basis (including co-factors) vitamin D will typically be taken daily.

Infrequent is often be better than daily

Better than Daily category listing has 30 items along with related searches

Unaware of any study which found that daily was best

Half-Life appears to vary with amount of vitamin D

Half-life = how long till half of the substance is gone (from the blood)
For people with a very low level of 10 nanograms, the response will fall by half in about 10 weeks
For people with a very high level of 50 nanograms, the response will fall by half in about 1 week

Notional chart of Vitamin D benefit vs dosing frequency for >50 nanograms

see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=2475
Note: Have not yet seen any study of vitamin D half-life. Would like to see one.


Response to a single dose of 100,000 IU of vitamin D

starting at 27 nanograms/ml, half life is about 50 days
see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=1046

short url = http://is.gd/D3weekly

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Created by admin. Last Modification: Thursday January 25, 2024 22:07:10 GMT-0000 by admin. (Version 71)
Take vitamin D3 daily, weekly, or bi-weekly        
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10452 Cocentration gradient.jpg admin 02 Sep, 2018 40.28 Kb 43674
10451 Which slide faster.jpg admin 02 Sep, 2018 29.58 Kb 62040
1144 Half-life notion.jpg admin 12 Mar, 2012 14.04 Kb 4272