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Shift work associated with lower Vitamin D in 12 of 13 studies – meta-analysis July 2022


Shift Work and Serum Vitamin D Levels: A Systematic Review and Meta-Analysis

Int. J. Environ. Res. Public Health 2022, 19(15), 8919; https://doi.org/10.3390/ijerph19158919
by Margherita Martelli 1,Gianmaria Salvio 2ORCID,Lory Santarelli 1,* andMassimo Bracci 1,*ORCID
1 Occupational Health, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy
2 Endocrinology Clinic, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60126 Ancona, Italy

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Vitamin D deficiency and insufficiency are highly prevalent conditions worldwide due to several factors, including poor sun exposure. Shift workers may be exposed to the risk of hypovitaminosis D due to fewer opportunities for sunlight exposure compared to day workers. A systematic review of the PubMed, SCOPUS, and EMBASE databases was conducted according to the Preferred Reporting Items for Systemic Reviews and Meta-Analyses (PRISMA) statement to investigate the effect of shift work on vitamin D levels. Mean differences (MD) and 95% confidence intervals (CI) of serum 25-OH-D levels in shift workers and non-shift workers were calculated. A total of 13 cross-sectional studies were included in the meta-analysis. We found significantly lower levels of serum 25-OH-D in shift workers compared with non-shift workers (MD: -1.85, 95% CI [-2.49 to -1.21]). Heterogeneity among included studies was high (I2 = 89%, p < 0.0001), and neither subgroup analysis nor meta-regression were able to identify specific sources of the heterogeneity that may be related to the different characteristics of shift work among studies. The monitoring of serum vitamin D levels and prompt correction of any deficiencies should be considered in shift workers. Notably, since a large part of the observations are derived from Koreans, larger epidemiological studies are needed in other populations.
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VitaminDWiki - High Risk category contains

64 items in High Risk Category

Those at high-risk of being Vitamin D deficient will require about 1.5X more vitamin D to restore their levels
Those who are at risk due to being obese need about 2X more vitamin D to restore their levels

see also
  Overview Dark Skin
  Overview Seniors
  Overview Obesity
  Overview Pregnancy
  Overview Deficiency
   Shut-in category which has 39 items
   Middle East category which has 149 items

22 VitaminDWiki pages had CLOTH in the title as of July 2022
14 VitaminDWiki pages with SHIFTWORK etc in title as of July 2022


VitaminDWiki pages with SHIFTWORK etc in title (14 as of July 2022)

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Items found: 15

Created by admin. Last Modification: Saturday July 23, 2022 00:15:23 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
18164 Shift table.jpg admin 22 Jul, 2022 17:22 50.86 Kb 105
18163 Shift Work and Vitamin D meta_CompressPdf.pdf PDF 2022 admin 22 Jul, 2022 17:21 605.17 Kb 56