Poor vision associated with poor Vitamin D or poor Vit. D genes – June 2022

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Vitamin D, the Vitamin D Receptor, Calcitriol Analogues and Their Link with Ocular Diseases

Nutrients 2022, 14(11), 2353; https://doi.org/10.3390/nu14112353
by Miłosz Caban and Urszula Lewandowska *ORCID
Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, Poland

PDF Table of Contents

Chart of vision and genes

Studies

The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents. One such agent is vitamin D, known to have a range of anti-cancer, anti-angiogenic, anti-inflammatory and anti-oxidative properties, and whose deficiency is linked to the pathogenesis of a range of cardiovascular, cancer, and inflammatory diseases. This review presents the current stage of knowledge concerning the link between vitamin D and its receptor and the occurrence of eye disease, as well as the influence of analogues of calcitriol, an active metabolite of vitamin D. Generally, patients affected by various ocular disorders have vitamin D deficiency. In addition, previous findings suggest that vitamin D modulates the course of eye diseases and may serve as a marker, and that its supplementation could mitigate some disorders. However, as these studies have some limitations, we recommend further randomized trials to clarify the link between vitamin D and its activity with eye disease.
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VitaminDWiki - Vision category starts contains

• 12% larger pupils in children who are Vitamin D deficient – Feb 2024 parasympathetic nervous system?
• Myopia, AMD, Dry Eye, and Diabetic Retinopathy are all associated with low Vitamin D - April 2023
• An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022
• Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019
• Vitamin D treats and prevents a variety of eye problems (need 70 ng) – June 2018
• Vitamin D and Myopia, AMD, Diabetic Retinopathy, Uveitis, Glaucoma, VDR etc. – May 2015
• Tears often have 25 % higher levels of vitamin D than does blood

Vision problems having many studies on VitaminDWiki

• Age-Related Macular Degeneration and Vitamin D - many studies
• Cataracts and Vitamin D - many studies
• Diabetic Retinopathy associated with low Vitamin D - many studies
• 7+ studies of Glaucoma and Vitamin D
• 21+ studies of Myopia and Vitamin D

101 items in Vision category

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VitaminDWiki - 8 studies in both categories Vision and VDR

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