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Perhaps Italians have air conditioning too: lower latitudes have less vitamin D – July 2013

Regional differences of vitamin D deficiency in rheumatoid arthritis patients in Italy.

Reumatismo. 2013 Jul 23;65(3):113-20. doi: 10.4081/reumatismo.2013.113.
Rossini M, D'Avola G, Muratore M, Malavolta N, Silveri F, Bianchi G, Frediani B, Minisola G, Sorgi ML, Varenna M, Foti R, Tartarelli G, Orsolini G, Adami S, Italian Society Of Rheumatology Sir OB.
Rheumatology Unit, University of Verona. maurizio.rossini at univr.it.

Vitamin D deficiency is very common in patients with rheumatoid arthritis (RA). Aim of this study was to evaluate the prevalence of vitamin D deficiency among the different Italian regions and whether these variations are associated with different severity of the disease. The study includes 581 consecutive RA patients (464 women), not taking vitamin D supplements, from 22 Italian rheumatology centres uniformly distributed across Italy. Together with parameters of disease activity (disease activity score 28), functional impairment (activities of daily living and health assessment questionnaire disability index) and mean sun exposure time, all patients had serum 25-hydroxyvitamin D (25OHD) measured in a centralized laboratory.

Vitamin D deficiency (25OHD level < 20 ng/mL) was very frequent among RA patients; its prevalence was 60%, 52% and 38% in southern, central and northern Italy, respectively. Mean disease activity and disability scores were worse in southern regions of Italy. These scores were inversely related to 25OHD levels and this correlation remained statistically significant after adjusting for both body mass index (BMI) and sun exposure time. However, disease severity remained significantly higher in southern regions versus central-northern Italy after adjustment also for serum 25OHD levels, age and BMI. In RA Italian patients there are significant regional differences in the prevalence of vitamin D deficiency explained by different BMI, and sun exposure time, and inversely associated with disease activity and disability scores.

PMID: 23884026

Chart from a report on the same study at the Vitamin D Council



Many places around the world are now able to totally avoid the hot summer sun by using air conditioning.
The Middle East, for example, avoids the summer sun so much that the flu comes in the summer instead of the winter.

The people living in the Southern portion of the US appear to be using air conditioning so much that the latitude affect of MS reversed by the middle of the century
Shows decrease of association of MS with latitude during 2oth century wars - probably due to people in the South being able to be indoors due to air conditioning

See also VitaminDWiki

Less Sun Less D Less Health

Attached files

ID Name Comment Uploaded Size Downloads
2884 RA Italy.jpg admin 08 Aug, 2013 45.27 Kb 1105
2843 Italy July.jpg admin 26 Jul, 2013 57.28 Kb 1581