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Omega-3 prevents Parkinson’s Disease – Review of RCT July 2019

Omega 3 fatty acids and neurodegenerative diseases: new evidence in clinical trials

www.preprints.org doi:10.20944/preprints201907.0289.v1 not yet peer reviewed
Rossella Avallone 1*, Giovanni Vitale 1 and Marco Bertolotti 2
Department of Life Sciences, Modena and Reggio Emilia University, 41125 Modena, Italy; rosseUa.avaUone at unimore.it (R.A.); giovanni.vitale at unimore.it (G.V.)
Division of Geriatric Medicine, Department of Biomedical, Metabolic and Neural Sciences, and Center for Gerontological Evaluation and Research, Modena and Reggio Emilia University, 41126 Modena, Italy; marco.bertolotti at unimore.it (M.B.)
* Correspondence: rossella.avallone at unimore.it; Tel.: +39-059-2055720 (R.A.)

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Abstract: A nutritional approach could be a promising strategy to prevent or slow the progression of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, since there is no effective therapy for these diseases so far. The beneficial effects of omega-3 fatty acids are now well established by a plethora of studies through their involvement in multiple biochemical functions, including synthesis of antinflammatory mediators, cell membrane fluidity, intracellular signalling and gene expression.
This systematic review will consider epidemiological studies and clinical trials that assessed the impact of supplementation or dietary intake of omega-3 polyunsaturated fatty acids on neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. Indeed, treatment with omega-3 fatty acids, being safe and well tolerated, represent a valuable and biologically plausible tool in the management of neurodegenerative diseases in their early stages.


Created by admin. Last Modification: Friday March 12, 2021 21:30:44 GMT-0000 by admin. (Version 4)

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ID Name Comment Uploaded Size Downloads
12418 Omega-3 neurodegen.pdf admin 01 Aug, 2019 834.04 Kb 488