Effects of influenza vaccine and sun exposure time against laboratory-confirmed influenza hospitalizations among young children during the 2012-13 to 2015-16 influenza seasons.
J Microbiol Immunol Infect. 2019 Oct 29. pii: S1684-1182(19)30166-5. doi: 10.1016/j.jmii.2019.09.010
Wang CY1, Chang YH2, Huang LM2, Chi H3, Chiu NC3, Chang LY2, Lu CY2, Huang YC4, Lin HC5, Lee JT6, Liu CC7, Huang YC8, Ho YH9, Tu YH10, Wang JY11, Huang DT12; Taiwan Pediatric Infectious Disease Alliance.
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Flu has the following
Vitamin D fights all phases of Influenza
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- CONCLUSION To help protect/suppress influenza, take 50,000 IU of Vitamin D once a week
during the flu season if you are an average weight adult
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Influenza is a major cause of acute respiratory infection burden worldwide, leading to many hospitalizations. An annual influenza vaccine is believed to be the best way to prevent influenza-related illnesses. We focused on the efficacies of other possible preventive measures such as increasing sun exposure time and dietary supplements to prevent these illnesses.
We conducted a matched-pair case-control study along with the Taiwan Pediatric Infectious Disease Alliance. We included influenza-related hospitalized patients with age ranging from 6 months to 5 years during the 2012-2013, 2013-2014, 2014-2015, and 2015-2016 influenza seasons. The controls were comparable to cases in age, sex, and residential area and had no influenza-related hospitalization records in the same season. We extracted data from vaccination histories and got the patients' guardians to complete questionnaires. Data were analyzed using conditional logistic regression.
We enrolled 1514 children (421 influenza-infected cases and 1093 controls) in the study. We found seasonal influenza vaccination to be an independent protective factor against hospitalizations owing to influenza [p < 0.01; odds ratio (OR), 0.427; 95% confidence interval (CI), 0.306-0.594]. Children with mean sun exposure time of >7 h/week had a significantly lower risk of influenza-related hospitalizations than those with the mean sun exposure time of ≤7 h/week (p < 0.05; OR, 0.667; 95% CI, 0.491-0.906).
Seasonal influenza vaccination effectively prevents influenza-related hospitalizations in children aged ≤5 years. Besides, >7 h of sun exposure/week may also be associated with lower risk of influenza-related hospitalizations in children.
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