Prenatal or Childhood Serum Levels of Vitamin D and Dental Caries in Paediatric Patients: A Systematic Review.
Oral Health & Preventive Dentistry, 03 Sep 2020, 18(1):653-667, DOI: 10.3290/j.ohpd.a45089
Carvalho Silva C, Mendes R, Manso MDC, Gavinha S, Melo P
20 most-recently changed items in Dental Category
- Severe infant caries 10X higher risk if low vitamin D (under 14 ng) - Dec 2021
- Virtually all infants in Poland got 400 IU of Vitamin D daily (not enough, non-daily is better) – April 2021
- More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
- Teeth from 19th century London indicate that most children were Vitamin D Deficient - Oct 2019
- Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT Aug 2019
- Half as many teeth problems if higher cord blood level of vitamin D – March 2019
- No tooth decay in children with adequate Vitamin D (small study) – June 2018
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
- Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D) – June 2017
- Dental Caries risk in children cut in half if more than 20 nanogram of Vitamin D – Nov 2015
- Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D – Dec 2014
- 3X fewer infant dental caries if good level of vitamin D while pregnant – April 2014
- Severe tooth decay in children unless supplemented with Vitamin D drops – Oct 2013
- UVB added in classroom reduced cavities, increased height, increased academics. etc
- Dental caries cut in half by vitamin D, review of 24 old clinical trials – Nov 2012
- Children with severe caries were 2X more likely to have inadequate vitamin D – July 2012
PURPOSE:To assess the association between low prenatal or childhood levels of 25-hydroxyvitamin D (25(OH) D) and dental caries experience in children. MATERIALS AND
METHODS:PubMed, B-On, Web of Science, Scopus, and Cochrane Library databases were searched. The inclusion criteria were randomised controlled trials, cohort and cross-sectional studies published between 1998 and 2019; caries outcomes expressed as prevalence or based on the decayed missing and filled index for primary and permanent teeth/surfaces; and vitamin D levels assessed by laboratory analysis. Two authors independently selected studies, collected data, and assessed risk of bias. The quality of the studies was also assessed. A narrative synthesis of the studies was performed without quantitative pooling of data due to clinical and methodological heterogeneity.
RESULTS:Out of 399 studies identified, 13 were included in the data synthesis. Even though many of the included studies had a cross-sectional design, 11 were considered high quality. The studies indicated that vitamin D has an important role in caries experience, but also revealed that vitamin D levels equal to or above 75 nmol/l seem to be more closely related to caries experience than the reference value of the Institute of Medicine.
CONCLUSION:Evidence of an association exists between low 25(OH) D levels (<75 nmol/l) and caries experience in children. Hence, low vitamin D levels should be considered a potential factor associated with caries in children. Clinicians should be aware that good prenatal nutrition and early childhood diet might influence caries experience.