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Mental health of children: vast majority of studies reviewed found that vitamin D helped – March 2021

The Influence of Vitamin D Intake and Status on Mental Health in Children: A Systematic Review

Nutrients. 2021 Mar 16;13(3):952. doi: 10.3390/nu13030952.
Dominika Głąbska 1, Aleksandra Kołota 1, Katarzyna Lachowicz 1, Dominika Skolmowska 1, Małgorzata Stachoń 1, Dominika Guzek 2


Mental Illness and Vitamin D

Anxiety studies include

14+ VitaminDWiki pages with ANXIETY in title
This list is automatically updated

Items found: 15
Title Modified
International Adolescent Anxiety and suicide rates - GBD April 2024 07 Apr, 2024
Half as much anxiety and sleep problems if get lots of vitamin D from food (excluded getting D from supplements) – Feb 2024 23 Feb, 2024
Anxiety, Vitamin D, Omega-3 - many studies 23 Feb, 2024
Low Vitamin D is associated with risk of Depression 5X, Stress 4.8 X, and Anxiety 3.9 X (Saudi Arabia college students) – July 2023 29 Jul, 2023
Parkinson’s – Vitamin D, bone density, insomnia, falls, poor sleep, anxiety – March 2019 10 May, 2023
Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022 22 Dec, 2022
Depression and Anxiety treatment with Vitamin D - probable molecular pathways - June 2022 21 Dec, 2022
Coronary Artery Disease Chest Pain, Anxiety, and Fatigue associated with low vitamin D – Oct 2022 07 Oct, 2022
Anxiety, depression, and suicide have recently surged (Note: Vitamin D, Omega-3, and Magnesium help) – May 2022 29 May, 2022
General Anxiety Disorder treated by weekly Vitamin D (50,000 IU -Omega-3, Mg also help) – Sept 2019 09 Dec, 2019
Omega-3 reduces Depression. Anxiety, Stress, PTSD, etc. – Aug 2018 02 Sep, 2019
Happy Nurses Project gave Omega-3 for 3 months – reduced depression, insomnia, anxiety, etc for a year – RCT July 2018 10 Nov, 2018
Anxiety severity reduced if more than 2 grams of Omega-3 – meta-analysis Sept 2018 19 Sep, 2018
Why is teen anxiety increasing so much (no mention of Magnesium, Vitamin D nor Omega-3) – Oct 2017 11 Oct, 2017
Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety – Nov 2014 11 Feb, 2015

Depression summary

Some recent publications

Studies in both categories ADHD and Children are listed here: 

 Download the PDF from VitaminDWiki

A potential role of vitamin D in some components of mental health is currently suggested, but the analyses are conducted mainly for adults, while for young individuals mental health is especially important, due to its lifelong effects. The aim of the study was to analyze the association between vitamin D intake or status and mental health in children within a systematic review of literature, including both intervention and observational studies. The literature search was conducted according to the PRISMA guidelines and it covered peer-reviewed studies included in databases of PubMed and Web of Science until October 2019. The studies presenting either vitamin D intake, or vitamin D status in human subjects were allowed (excluding subjects with intellectual disabilities, eating disorders and neurological disorders), while for mental health the various methods of assessment and wide scope of factors were included. The bias was assessed using the Newcastle-Ottawa Scale (NOS). The review was registered in the PROSPERO database (CRD42020155779).
A number of 7613 studies after duplicate removing were extracted by two independent researchers, followed by screening and assessment for eligibility, conducted by two independent researchers in two steps (based on title and abstract). Afterwards, the full texts were obtained and after reviewing, a number of 24 studies were included. The synthetic description of the results was prepared, structured around exposure (vitamin D supplementation/status) and outcome (components of mental health).
The included studies were conducted either in groups of healthy individuals, or individuals with mental health problems, and they assessed following issues:

  • behavior problems,
  • violence behaviors,
  • anxiety,
  • depressive symptoms/depression,
  • aggressive disorder,
  • psychotic features,
  • bipolar disorder,
  • obsessive compulsive disorder,
  • suicidal incident,
  • as well as general patterns, as follows:
    • mental health, level of distress, quality of life, well-being, mood, sleep patterns.

The vast majority of assessed studies, including the most prominent ones (based on the NOS score) supported potential positive influence of vitamin D on mental health in children. As a limitation of the analysis, it should be indicated that studies conducted so far presented various studied groups, outcomes and psychological measures, so more studies are necessary to facilitate comparisons and deepen the observations. Nevertheless, vitamin D intake within a properly balanced diet or as a supplementation, except for a safe sun exposure, should be indicated as an element supporting mental health in children, so it should be recommended to meet the required 25(OH)cholecalciferol blood level in order to prevent or alleviate mental health problems.
From PDF
The summary of observations and conclusions for included studies of association between vitamin D and mental health, with the total NOS score are described in Table 10. It was observed that for the vast majority of included studies, both intervention and observational ones, the results supported beneficial association.
Only in case of 2 studies, no effect of vitamin D was stated for bipolar disorder and major depressive disorder [51] and mental health (assessed using DSM-V criteria) [55].
In case of three studies the effect of vitamin D was inconclusive, as it was observed only for some of applied analysis [50,60] or depending on the studied component of obsessive compulsive disorder [52]. However, while the total NOS score is taken into account, it should be indicated that all the studies of low risk of bias support the positive effect of vitamin D [47,62,63].

Created by admin. Last Modification: Saturday April 3, 2021 23:06:18 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
15366 MH results.jpg admin 03 Apr, 2021 183.07 Kb 346
15365 Mental health children review.pdf admin 03 Apr, 2021 677.69 Kb 388