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Long-haul COVID-19 - another hint that Vitamin D should help - Dec 2020

"End of 2020 COVID19 Immunology Recap - PLUS - Special Update for Long-Haulers"
Dr. Patterson attributes long-haul COVID19 to the absence of germinal centers and reports a low CD8 T-cell signature:
See Minute 16 and min 40-49 ("when patients were getting better CD8+T-cells were going UP"):
Remember: CD8+T-cells have the highest amount of the vit D receptor of all immune cells

CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis - 2012
"Here it is proposed that this CD8+ T-cell deficiency underlies the development of chronic autoimmune diseases by impairing CD8+ T-cell control of Epstein-Barr virus (EBV) infection, with the result that EBV-infected autoreactive B cells accumulate in the target organ where they produce pathogenic autoantibodies and provide costimulatory survival signals to autoreactive T cells which would otherwise die in the target organ by activation-induced apoptosis. Autoimmunity is postulated to evolve in the following steps: (1) CD8+ T-cell deficiency, (2) primary EBV infection, (3) decreased CD8+ T-cell control of EBV. It is also proposed that deprivation of sunlight and vitamin D at higher latitudes facilitates the development of autoimmune diseases by aggravating the CD8+ T-cell deficiency and thereby further impairing control of EBV.
 Download the PDF from VitaminDWiki
Thanks goes to Hilja Gebest for finding this


See also VitaminDWiki

Items in both categories Virus and Vitamin D Receptor are listed here:

The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019

Vitamin D Receptor activation can be increased by any of: Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise,   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators


See "long-haul" in VitaminDWiki titles

Items found: 7



Created by admin. Last Modification: Friday May 7, 2021 12:21:10 GMT-0000 by admin. (Version 5)

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15444 CD8+ T-Cell Deficiency.pdf admin 16 Apr, 2021 13:36 2.33 Mb 33
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