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Hip fracture outcome 5X more likely to be poor if low vitamin D – Jan 2015

Serum levels of 25-hydroxyvitamin D and functional outcome among postmenopausal women with hip fracture.

PLoS One. 2015 Jan 30;10(1):e0116375. doi: 10.1371/journal.pone.0116375. eCollection 2015.
Liu LM1, Wang SH1, Fu CS1, Han XZ1, Wei BF2.

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OBJECTIVE:
The main objective of the current study was to assess the distribution and its prognostic value of serum 25-hydroxyvitamin D (25[OH] D) levels assessed at admission in Chinese postmenopausal women with hip fracture.

METHODS:
From January 1, 2012 to December 31, 2013, all postmenopausal women with first-ever hip fracture were recruited to participate in the study. Serum 25[OH] D levels were measured at admission. The functional evaluation at the time of discharge was performed by the Barthel Index (BI). The prognostic value of 25[OH] D to predict the functional outcome within discharge was analyzed by logistic regression analysis, after adjusting for the possible confounders.

RESULTS:
In our study, 261 patients were included and assessed. In the 76 patients with an unfavorable functional outcome, serum 25(OH) D levels were lower compared with those in patients with a favorable outcome [11.8(IQR, 9.9-16.1) ng/ml; 16.8(IQR, 13.6-21.4) ng/ml, respectively; P<0.0001].
In multivariate analysis, there was an increased risk of unfavorable outcome associated with serum 25(OH) D levels ≤ 20 ng/ml (OR 5.24, 95%CI: 3.11-8.15; P<0.0001) after adjusting for possible confounders.

CONCLUSIONS:
Our data support an association between serum 25[OH] D levels and prognosis in Chinese postmenopausal women with hip fracture.

PMID: 25635882

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Note: Most people can eliminate even having a hip fracture in the first place by having vitamin D > 40 ng

See also VitaminDWiki

Pages listed in BOTH the categories Falls/Fracture and Meta-analysis

Attached files

ID Name Comment Uploaded Size Downloads
5183 Barthel Index.jpg admin 16 Mar, 2015 31.00 Kb 1050
5182 Hip Fracture Outcome F2.jpg admin 16 Mar, 2015 20.01 Kb 999
5181 Hip Fracture Outcome.pdf admin 16 Mar, 2015 306.07 Kb 975