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Half of Cystic Fibrosis patients have low Magnesium levels – April 2022


Magnesium Status and Calcium/Magnesium Ratios in a Series of Cystic Fibrosis Patients

Nutrients 2022, 14(9), 1793; https://doi.org/10.3390/nu14091793 (registering DOI)
by Marlene Fabiola Escobedo-Monge 1,*ORCID,Enrique Barrado 2,Joaquín Parodi-Román 3,María Antonieta Escobedo-Monge 4ORCID,Marianela Marcos-Temprano 5 andJosé Manuel Marugán-Miguelsanz 1,6

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Magnesium (Mg) is an essential micronutrient that participates in various enzymatic reactions that regulate vital biological functions. The main aim was to assess the Mg status and its association with nutritional indicators in seventeen cystic fibrosis (CF) patients. The serum Mg and calcium (Ca) levels were determined using standardized methods and the dietary Mg intake by prospective 72 h dietary surveys.
The mean serum Ca (2.45 mmol/L) and Mg (0.82 mmol/L) had normal levels, and the mean dietary intake of the Ca (127% DRI: Dietary Reference Intake) and Mg (125% DRI) were high.
No patients had an abnormal serum Ca.
A total of 47% of the subjects had hypomagnesemia and 12% insufficient Mg consumption. One patient had a serum Mg deficiency and inadequate Mg intake.
A total of 47 and 82% of our series had a high serum Ca/Mg ratio of >4.70 (mean 4.89) and a low Ca/Mg intake ratio of <1.70 (mean 1.10), respectively.
The likelihood of a high Ca/Mg ratio was 49 times higher in patients with a serum Mg deficiency than in normal serum Mg patients.
Both Ca/Mg ratios were associated with the risk of developing

  • cardiovascular disease (CVD),
  • type 2 diabetes (T2D),
  • metabolic syndrome (MetS), and even
  • several cancers.

Therefore, 53% of the CF patients were at high risk of a Mg deficiency and developing other chronic diseases.
 Download the PDF from VitaminDWiki


Appears that Cystic Fibrosis needs Vitamin D, Magnesium, Vitamin K2, etc.

"The sticky mucus from cystic fibrosis can block normal absorption of key nutrients and fat in the intestines, causing: poor digestion"
need Gut-Friendly Vitamin D etc.


VitaminDWiki - 3 studies in both categories Cystic Fibrosis and Magnesium

This list is automatically updated


VitaminDWiki - 28 studies in both categories Magnesium and Calcium

This list is automatically updated


Created by admin. Last Modification: Friday September 9, 2022 20:17:09 GMT-0000 by admin. (Version 11)

Attached files

ID Name Comment Uploaded Size Downloads
17493 Mg CF.jpg admin 25 Apr, 2022 34.49 Kb 237
17492 Mg vs CF years.jpg admin 25 Apr, 2022 60.40 Kb 277
17491 Magnesium Cystic Fibrosis_CompressPdf.pdf admin 25 Apr, 2022 444.12 Kb 196